| Type | Description |
|---|---|
| Definition | patched 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:13:00 | [Exploring parent-of-origin effects for non-syndromic cleft lip with or without cleft palate on PTCH1, PTCH2, SHH, SMO genes in Chinese case-parent trios]. | 33047712 |
| 2020-05-30 13:05:00 | Pds5b/Ptch2 axis regulates cell proliferation and invasion in pancreatic tumor cells. | 31233836 |
| 2020-03-07 11:32:00 | The importance of the ATRX/DAXX pathway was confirmed by the first-ever pancreatic neuroendocrine neoplasms (pNEN)-specific protein-damaging hotspot mutation in DAXX. In this study, both novel genes, including the pro-apoptotic CYFIP2 gene and hedgehog signaling PTCH2, and novel pathways, such as the MAPK-ERK pathway, were implicated in pNEN. | 30021865 |
| 2019-07-13 11:46:00 | Our data extend these observations and demonstrate a significant increase in Ptch2 expression in the obstructive UPJ segments in a subset of patients with congenital UPJO. | 29109083 |
| 2018-12-22 11:22:00 | Combined heterozygous germline mutations in PTCH1 and PTCH2 were identified in a patient with embryonal rhabdomyosarcoma. | 29230040 |
| Type | IDs |
|---|---|
| Synonymous | PTC2 |
| Gene |
UniProtKB-ID:
PTC2_HUMAN
UniprotKB:
Q9Y6C5
UniParc:
UPI00001328B8,
UPI000002B1C9
EMBL:
AF091501,
AY358555,
AL136380,
AF087651,
AY438664,
AL592166,
AY359016,
AF119569
Ensembl:
ENSG00000117425
KO:
hsa:8643
|
| Nucleutide sequences |
EMBL-CDS:
AAR05447.1,
AAD17260.1,
AAQ89375.1,
AAC79847.1,
AAQ88919.1,
AAD25953.1
Gene_ORFName:
UNQ560/PRO1121/PRO57079
Ensembl_TRS:
ENST00000447098,
ENST00000372192
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000389703,
ENSP00000361266
RefSeq:
NP_001159764.1,
NP_003729.3
|
| Others |
UniRef100:
UniRef100_Q9Y6C5
UniRef90:
UniRef90_Q9Y6C5
UniRef50:
UniRef50_Q9Y6C5
UniGene:
Hs.591497
CCDS:
CCDS516.1,
CCDS53312.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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