| Type | Description |
|---|---|
| Definition | 2'-5'-oligoadenylate synthetase like |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 10:57:00 | OASL regulates pro-inflammatory mediators such as cytokines and chemokines which suppress intracellular mycobacterial growth and survival. | 31855809 |
| 2019-07-06 10:03:00 | these resulta define distinct mechanisms by which OASL differentially regulates host IFN responses during RNA and DNA virus infection and identify OASL as a negative-feedback regulator of cGAS | 30635239 |
| 2017-06-10 11:55:00 | These data uncover a promycobacterial role for STING-dependent OASL production during Mycobacterium leprae infection that directs the host immune response toward a niche that permits survival of the pathogen. | 27190175 |
| 2015-12-05 10:12:00 | OASL acts as a cellular antiviral protein and RSV NS1 suppresses this function to evade cellular innate immunity and allow virus growth. | 26178980 |
| 2014-10-04 12:49:00 | Primary mononuclear cells from patients with systemic sclerosis have increased basal levels of OASL and OAS2 genes. | 24328427 |
| Type | IDs |
|---|---|
| Synonymous | OASL1, OASLd, TRIP-14, TRIP14, p59 OASL, p59-OASL, p59OASL |
| Gene |
UniProtKB-ID:
OASL_HUMAN
UniprotKB:
Q15646
UniParc:
UPI000002B00A,
UPI00025D998A,
UPI000005339E
EMBL:
AF063611,
AK314419,
Z93097,
AF063612,
AJ225089,
AC079602,
JQ792168,
L40387,
BC117410,
BC117408
Ensembl:
ENSG00000135114
KO:
hsa:8638
|
| Nucleutide sequences |
EMBL-CDS:
CAA12396.1,
BAG37039.1,
AFJ00074.1,
AAD28541.1,
AAC41733.1,
AAI17411.1,
AAI17409.1,
AAD28542.1
Ensembl_TRS:
ENST00000339275,
ENST00000620239,
ENST00000257570
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000479512,
ENSP00000341125,
ENSP00000257570
RefSeq:
NP_003724.1,
NP_937856.1,
NP_001248754.1,
XP_016875629.1,
XP_016875630.1
|
| Others |
UniRef100:
UniRef100_Q15646
UniRef90:
UniRef90_Q15646
UniRef50:
UniRef50_Q15646
UniGene:
Hs.118633
CCDS:
CCDS9212.1,
CCDS9211.1,
CCDS73536.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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