| Type | Description |
|---|---|
| Definition | src kinase associated phosphoprotein 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-07-01 10:16:00 | K152 and D120 within the PH domain of SKAP55 regulate plasma membrane targeting and T cell receptor-mediated activation of LFA-1. | 28052935 |
| 2014-04-12 10:43:00 | SKAP55 dimers stabilize SLP-76 microclusters, couple SLP-76 to the force-generating systems responsible for microcluster movement, and enable adhesion via the TCR by mechanisms independent of RIAM, talin, and beta1 integrins. | 24368808 |
| 2012-06-16 11:29:00 | single-nucleotide polymorphisms in ARRDC3, FLT1, and SKAP1 were significant predictors for survival androgen-deprivation therapy in prostate cancer patients. | 21652578 |
| 2011-10-22 11:14:00 | N-terminal myr-tagged SKAP1 for membrane binding facilitated constitutive RapL membrane and Rap1 binding and effectively substituted for PI3K and TCR ligation in the activation of LFA-1 in T cells. | 21669874 |
| 2010-12-05 22:09:00 | Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | 20852632 |
| Type | IDs |
|---|---|
| Synonymous | HEL-S-81p, SCAP1, SKAP55 |
| Gene |
UniProtKB-ID:
SKAP1_HUMAN,
V9HW03_HUMAN
UniprotKB:
Q86WV1,
V9HW03
UniParc:
UPI0000200EFD,
UPI000000DC66
EMBL:
AC036222,
Y11215,
BC047870,
AC027152,
AC090627,
AC006468,
CH471109,
EU668346
Ensembl:
ENSG00000141293
KO:
hsa:8631
|
| Nucleutide sequences |
EMBL-CDS:
CAA72101.1,
EAW94749.1,
EAW94750.1,
AAH47870.1,
EAW94747.1,
ACF94499.1
Gene_ORFName:
hCG_29349
Ensembl_TRS:
ENST00000584924,
ENST00000336915
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000338171,
ENSP00000464311
RefSeq:
XP_016880746.1,
XP_016880748.1,
XP_024306780.1,
XP_016880747.1,
XP_005257812.1,
NP_001068567.1,
XP_016880749.1,
NP_003717.3
|
| Others |
UniRef100:
UniRef100_Q86WV1,
UniRef100_V9HW03
UniRef90:
UniRef90_Q86WV1
UniRef50:
UniRef50_Q86WV1
UniGene:
Hs.316931
CCDS:
CCDS32674.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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