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863 CBFA2T3

863

CBFA2T3

CBFA2/RUNX1 translocation partner 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition CBFA2/RUNX1 translocation partner 3

研究结论

Date Results Publications
2021-01-16 15:54:00 The transcriptional corepressor CBFA2T3 inhibits all-trans-retinoic acid-induced myeloid gene expression and differentiation in acute myeloid leukemia. 32434928
2020-11-21 13:28:00 Embryonic erythropoiesis and hemoglobin switching require transcriptional repressor ETO2 to modulate chromatin organization. 32960220
2020-08-15 18:45:00 These findings suggest rs13333659 in CBFA2T3 as a risk locus to modulate the decline rate of cerebrospinal fluid amyloid-beta42 peptide preceding the onset of clinical symptoms 31370031
2020-05-16 12:07:00 CBFA2T3 is functional in t(8;21) acute myeloid leukemia cells, a possible RUNX1-RUNX1T1-mediated direct interference of CBFA2T3 corepressor function may be compensated by a higher threshold level of CBFA2T3 expression that is needed to drive the relapse of t(8;21) acute myeloid leukemia. 31040112
2019-12-21 11:56:00 Kaiso modifies MTG16-driven inflammation and tumorigenesis; this suggests that Kaiso deregulation contributes to MTG16-dependent colitis and Colitis-associated carcinoma phenotypes. 30858547

名称对应

Type IDs
Synonymous ETO2, MTG16, MTGR2, RUNX1T3, ZMYND4
Gene
UniProtKB-ID: MTG16_HUMAN
UniprotKB: O75081
UniParc: UPI0000167F93, UPI000007392A, UPI00015D775E, UPI00015D775F
EMBL: AF052217, AB010420, AF052215, AF052214, AF052220, CH471184, AF052216, BC047019, AB010419, AF052213, AB013286, BC062624
Ensembl: ENSG00000129993
KO: hsa:863
Nucleutide sequences
EMBL-CDS: AAH47019.1, AAC64701.1, BAA29061.1, AAC64702.1, BAA31276.1, EAW66752.1, EAW66748.1, AAC64698.1, BAA31277.1, BAA29062.1, AAH62624.1
Ensembl_TRS: ENST00000268679, ENST00000327483
Protein sequencees
Ensembl_PRO: ENSP00000332122, ENSP00000268679
RefSeq: NP_787127.1, XP_005256380.1, NP_005178.4, XP_024306244.1, XP_011521721.1
Others
UniRef100: UniRef100_O75081
UniRef90: UniRef90_O75081
UniRef50: UniRef50_O75081
UniGene: Hs.513811
CCDS: CCDS10972.1, CCDS10973.1

全选

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