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856926 DMC1

856926

DMC1

recombinase DMC1

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition recombinase DMC1

研究结论

Date Results Publications
2020-08-29 12:48:00 Rad51 facilitates filament assembly of meiosis-specific Dmc1 recombinase. 32404423
2020-08-22 15:26:00 Two auxiliary factors promote Dmc1-driven DNA strand exchange via stepwise mechanisms. 32414915
2020-02-29 10:04:00 In spite of its ability to load onto single-stranded DNA and carry out recombination in the absence of Mei5-Sae3, recombination promoted by the Dmc1 mutant is abnormal in that it forms foci in the absence of DNA breaks, displays unusually high levels of multi-chromatid and intersister joint molecule intermediates, as well as high levels of ectopic recombination products. 31790385
2019-08-24 11:59:00 RPA is particularly important for the high level of Dmc1 activity in a reconstituted system, with three distinct mechanisms contributing to RPA's overall activity. 30462332
2019-01-12 10:51:00 propose that Rad51 and Dmc1 have intrinsic capacities to form spatially distinct filaments, suggesting that additional recombination cofactors are not required to segregate the Rad51 and Dmc1 filaments 29382724

名称对应

Type IDs
Synonymous ISC2
Gene
UniProtKB-ID: DMC1_YEAST
UniprotKB: P25453
UniParc: UPI0000030744
EMBL: D10865, BK006939, M87549, U18922
EnsemblGenome: YER179W
KO: sce:YER179W
Nucleutide sequences
EMBL-CDS: AAA34571.1, DAA07842.1, AAB64706.1, BAA01637.1
EnsemblGenome_TRS: YER179W_mRNA
Protein sequencees
EnsemblGenome_PRO: YER179W
RefSeq: NP_011106.1
Others
UniRef100: UniRef100_P25453
UniRef90: UniRef90_P25453
UniRef50: UniRef50_P25453

全选

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研究热度

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