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856919 BRR2

856919

BRR2

ATP-dependent RNA helicase BRR2

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition ATP-dependent RNA helicase BRR2

研究结论

Date Results Publications
2016-12-17 11:18:00 Data show that the truncation of the first 247 amino acids of the N terminus in Bad Response to Refrigeration 2 (Delta247-Brr2) weakened RNA binding, reduced helicase activity, and reduced ATPase activity compared with wild type Brr2. 27072132
2016-04-23 11:54:00 the N-terminal region autoinhibits Brr2 via substrate competition and conformational clamping 26637280
2015-06-27 10:22:00 The N-terminal domain iscritical for retaining U5 and U6 snRNPs during/after spliceosomal activation through its interaction with snRNAs and other spliceosomal proteins, revealing a role of Brr2 in spliceosomal activation in addition to U4/U6 unwinding. 25670679
2014-05-10 10:12:00 We propose that the U5 snRNA IL1 is a platform for protein binding and is required for , Brr2 and Snu114 association with the U5 snRNA to form the U5 snRNP. 23857713
2014-02-22 13:04:00 Sad1 maintains the integrity of the tri-snRNP by counteracting Brr2-mediated dissociation of tri-snRNP. 24190974

名称对应

Type IDs
Synonymous PRP44, RSS1, SLT22, SNU246
Gene
UniProtKB-ID: BRR2_YEAST
UniprotKB: P32639
UniParc: UPI0000126AE4
EMBL: U18922, BK006939
EnsemblGenome: YER172C
KO: sce:YER172C
Nucleutide sequences
EMBL-CDS: AAB64699.1, DAA07834.1
Gene_ORFName: SYGP-ORF66
EnsemblGenome_TRS: YER172C_mRNA
Protein sequencees
EnsemblGenome_PRO: YER172C
RefSeq: NP_011099.1
Others
UniRef100: UniRef100_P32639
UniRef90: UniRef90_P32639
UniRef50: UniRef50_P32639

全选

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研究热度

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