| Type | Description |
|---|---|
| Definition | polyadenylate-binding protein |
| Date | Results | Publications |
|---|---|---|
| 2019-05-18 11:46:00 | The level of Pab1 binding to poly(A)-containing isoforms is surprisingly variable, and differences in Pab1 binding correlate with the extent of structural variation for closely spaced isoforms. | 30318446 |
| 2018-05-19 12:01:00 | The authors found that Pab1 association into these aggregates relies mainly on RNA recognition motifs, whose number is important for an efficient recruitment of the protein. | 28873979 |
| 2017-12-30 10:15:00 | Two distal RNA recognition motif of Sbp1 bind to the poly(A) sequence in the 5'UTR of the Pab1 mRNA specifically and cooperatively while the central RGG domain of the protein interacts directly with Pab1. | 28986506 |
| 2017-06-10 12:28:00 | Study shows that Pab1 phase separates and gels in response to physiological thermal and pH stresses, a demixing process, which is modulated by the P domain but does not require it; Poly(A)-binding protein thus acts as a physiological stress sensor, exploiting phase separation to precisely mark stress onset, a broadly generalizable mechanism. | 28283059 |
| 2015-12-19 10:10:00 | Closed-loop model of mRNA translation is prevalent for eIF4E/4G-bound but unexpectedly sparse for PAB1-bound mRNAs. | 25826658 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PABP_YEAST
UniprotKB:
P04147
UniParc:
UPI0000052E24
EMBL:
M12780,
D00023,
AY692854,
M13371,
BK006939,
U18922
EnsemblGenome:
YER165W
KO:
sce:YER165W
|
| Nucleutide sequences |
EMBL-CDS:
AAT92873.1,
AAA34787.1,
AAB64692.1,
AAA34838.1,
DAA07827.1,
BAA00017.1
EnsemblGenome_TRS:
YER165W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YER165W
RefSeq:
NP_011092.1
|
| Others |
UniRef100:
UniRef100_P04147
UniRef90:
UniRef90_P04147
UniRef50:
UniRef50_P04147
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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