| Type | Description |
|---|---|
| Definition | phosphatidylinositol-binding protein SCS2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:27:00 | ORP/Osh mediate cross-talk between ER-plasma membrane contact site components and plasma membrane SNAREs. | 32734583 |
| 2018-12-22 12:14:00 | Cells lacking Scs2/Scs22 performed spindle positioning via MT end capture-shrinkage mechanism, requiring dynein anchorage to an ER- and mitochondria-independent population of Num1, dynein motor activity, and CAP-Gly domain of dynactin Nip100/p150(Glued) subunit. Additionally, a CAAX-targeted Num1 rescued loss of lateral patches and MT sliding in the absence of Scs2/Scs22 | 30084355 |
| 2017-12-23 12:03:00 | Data suggest that a specific pool of phosphatidic acid, associated with lipid droplet formation in perinuclear ER, is responsible for initial rapid exit of Opi1p from nucleus to ER and is required for Ino1 expression in presence of choline; interaction between Opi1p and Scs2p in ER membrane facilitates transit of phosphatidic acid from ER to mitochondria. | 28924045 |
| 2017-09-30 13:58:00 | The deletion of SCS2 did not affect Ca2+ influx activity when calcineurin was inhibited by FK506, but enhanced this activity by 35% when the enzyme was not inhibited. However, this enhancement was canceled by the deletion of ECM7. These results suggest that Cch1/Mid1 is regulated differentially by Ecm7 and Scs2 in a manner that is dependent on the phosphorylation status of Cch1. | 28742147 |
| 2016-09-03 10:11:00 | this study examined the effects of Scs2p levels on the association of Opi1p with the nuclear membrane by both morphologically and biochemically. | 26590299 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SCS2_YEAST
UniprotKB:
P40075
UniParc:
UPI0000052E49
EMBL:
U18916,
D44493,
BK006939,
AY693125
EnsemblGenome:
YER120W
KO:
sce:YER120W
|
| Nucleutide sequences |
EMBL-CDS:
AAT93144.1,
DAA07780.1,
BAA07936.1,
AAC03218.1
EnsemblGenome_TRS:
YER120W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YER120W
RefSeq:
NP_011046.3
|
| Others |
UniRef100:
UniRef100_P40075
UniRef90:
UniRef90_P40075
UniRef50:
UniRef50_P40075
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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