| Type | Description |
|---|---|
| Definition | SUMO-targeted ubiquitin ligase complex subunit SLX8 |
| Date | Results | Publications |
|---|---|---|
| 2020-01-11 10:57:00 | Co-localization of the budding yeast STUbL Slx5/Slx8 and ubiquitin at seven genomic loci termed "ubiquitin hotspots" contribute to stress tolerance. | 31015336 |
| 2015-07-25 11:10:00 | RecQ-like helicase Sgs1 subcellular localization is regulated by SUMO-targeted ubiquitin ligase Slx5-Slx8 in response to DNA damage, presumably to prevent illegitimate recombination events. | 25588990 |
| 2010-01-21 00:00:00 | the DNA-damage targeting of Slx5/Slx8 depends on formation of the heterodimer and that this occurs at a subset of nuclear foci also containing DNA damage repair and checkpoint factors. | 19270524 |
| 2010-01-21 00:00:00 | Slx8 and Slx5 complex is capable of interacting directly with the SUMO pathway | 17669696 |
| 2010-01-21 00:00:00 | Data suggest that, during replication, the Slx5-Slx8 complex helps prevent DNA lesions that are acted upon by recombination, and inhibits Rad51-independent recombination via modulating the sumoylation of DNA repair proteins. | 17591698 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SLX8_YEAST
UniprotKB:
P40072
UniParc:
UPI000013ACBE
EMBL:
BK006939,
U18916
EnsemblGenome:
YER116C
KO:
sce:YER116C
|
| Nucleutide sequences |
EMBL-CDS:
AAC03214.1,
DAA07776.1
EnsemblGenome_TRS:
YER116C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YER116C
RefSeq:
NP_011041.3
|
| Others |
UniRef100:
UniRef100_P40072
UniRef90:
UniRef90_P40072
UniRef50:
UniRef50_P40072
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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