| Type | Description |
|---|---|
| Definition | GET complex subunit GET2 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-02 12:02:00 | GET 1, 2, 3 proteins target MOM proteins to the endoplasmic reticulum. | 29661846 |
| 2018-12-01 11:46:00 | Mitophagy during prolonged respiratory growth is strongly impaired in cells lacking Get1/2, a transmembrane complex mediating insertion of tail-anchored (TA) proteins into the endoplasmic reticulum (ER) membrane. Under the same conditions, loss of Get1/2 caused only slight defects in other types of selective and bulk autophagy. | 29673596 |
| 2016-12-17 12:11:00 | The authors show that endoplasmic reticulum membrane proteins Get1p and Get2p are required for maintaining normal levels of cardiolipin. | 26926495 |
| 2014-10-25 11:43:00 | identification of mutations in the Get1/2 transmembrane domain that disrupt tail-anchored protein insertion without interfering with Get1/2 cytosolic domain function | 25043001 |
| 2011-08-20 10:49:00 | crystal structures of Get3 in complex with cytosolic domain of Get1 and Get2 in different states; data show Get1 and Get2 can bind simultaneously to Get3;docking to Get1/2 complex allows for conformational change in Get3 required for TA protein insertion | 21719644 |
| Type | IDs |
|---|---|
| Synonymous | HUR2, RMD7 |
| Gene |
UniProtKB-ID:
GET2_YEAST
UniprotKB:
P40056
UniParc:
UPI00001D477B
EMBL:
U18839,
BK006939
EnsemblGenome:
YER083C
KO:
sce:YER083C
|
| Nucleutide sequences |
EMBL-CDS:
AAB64638.1,
DAA07744.1
EnsemblGenome_TRS:
YER083C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YER083C
RefSeq:
NP_011006.2
|
| Others |
UniRef100:
UniRef100_B3LRK1
UniRef90:
UniRef90_B3LRK1
UniRef50:
UniRef50_B3LRK1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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