| Type | Description |
|---|---|
| Definition | ribonucleotide-diphosphate reductase subunit RNR1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:08:00 | The yeast Aft1 transcription factor activates ribonucleotide reductase catalytic subunit RNR1 in response to iron deficiency. | 32147528 |
| 2019-08-31 13:16:00 | We identified 24 rnr1 mutant alleles resulting in diverse mutator phenotypes linked in most cases to imbalanced dNTPs. Among the identified rnr1 alleles the strongest mutators presented a dNTP imbalance in which three out of the four dNTPs were elevated (dCTP, dTTP and dGTP), particularly if dGTP levels were highly increased. | 30462295 |
| 2017-09-23 13:08:00 | Fhl1p regulates RNR1 gene transcription to maintain dNTP levels, thus modulating longevity by protection against replication stress | 28495531 |
| 2017-04-29 11:08:00 | Multiple turnover kinetics show that Sml1 inhibition of dGTP/ADP- and ATP/CDP-bound ScRR follows a mixed inhibition mechanism. However, Sml1 cooperatively binds to the ES complex in the dGTP/ADP form, whereas with ATP/CDP, Sml1 binds weakly and noncooperatively | 27155231 |
| 2013-08-10 11:51:00 | there is a directed orientation of the RNR beta and beta' C-terminal tails relative to alpha within the holoenzyme consistent with a docking model of the two subunits and argue against RT across the beta beta' interface | 23532842 |
| Type | IDs |
|---|---|
| Synonymous | CRT7, RIR1, SDS12 |
| Gene |
UniProtKB-ID:
RIR1_YEAST
UniprotKB:
P21524
UniParc:
UPI0000133974
EMBL:
X69216,
X69217,
BK006939,
U18813
EnsemblGenome:
YER070W
KO:
sce:YER070W
|
| Nucleutide sequences |
EMBL-CDS:
CAA49151.1,
AAB64606.1,
CAA49150.1,
DAA07729.1
EnsemblGenome_TRS:
YER070W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YER070W
RefSeq:
NP_010993.1
|
| Others |
UniRef100:
UniRef100_P21524
UniRef90:
UniRef90_P21524
UniRef50:
UniRef50_P21524
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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