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856799 MOT2

856799

MOT2

CCR4-NOT core ubiquitin-protein ligase subunit MOT2

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition CCR4-NOT core ubiquitin-protein ligase subunit MOT2

研究结论

Date Results Publications
2019-09-07 12:18:00 findings demonstrate that Ccr4-Not controls the ubiquitylation and turnover of Rpb1, the largest subunit of RNAPII, during transcription arrest 30948432
2015-10-03 10:32:00 Not4 is required for global translational repression under nutritional limitations and especially for repression of mRNAs that cause transient ribosome stalling. 25971775
2013-04-06 13:09:00 results identify a stress-induced proteolytic pathway regulating cyclin C that requires nuclear to cytoplasmic relocalization and Not4p-mediated ubiquitylation 22421358
2012-11-17 11:11:00 Screening a variety of mutants involved in ubiquitin-mediated proteolysis demonstrated an important role for the nuclear ubiquitin ligase Not4 in Yap1 degradation. Not4 was found to bind to Yap1 in an oxidant-stimulated fashion 22707721
2012-05-19 11:43:00 Not4 is required for appropriate association of the Not5 subunit of the Ccr4-Not complex with polysomes and for ubiquitination of Rps7A. 22243599

名称对应

Type IDs
Synonymous NOT4, SIG1
Gene
UniProtKB-ID: NOT4_YEAST
UniprotKB: P34909
UniParc: UPI0000052DFE
EMBL: M96736, U18813, BK006939, L26309
EnsemblGenome: YER068W
KO: sce:YER068W
Nucleutide sequences
EMBL-CDS: DAA07727.1, AAC37413.1, AAB00326.1, AAB64604.1
EnsemblGenome_TRS: YER068W_mRNA
Protein sequencees
EnsemblGenome_PRO: YER068W
RefSeq: NP_010991.3
Others
UniRef100: UniRef100_P34909
UniRef90: UniRef90_P34909
UniRef50: UniRef50_P34909

全选

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