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856739 ISC1

856739

ISC1

inositol phosphosphingolipid phospholipase

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition inositol phosphosphingolipid phospholipase

研究结论

Date Results Publications
2020-08-29 12:48:00 Yeast Sphingolipid Phospholipase Gene ISC1 Regulates the Spindle Checkpoint by a CDC55-Dependent Mechanism. 32205408
2018-07-14 11:43:00 results suggest that Sch9p pathways modulate acetic acid-induced cell death, through the regulation of Isc1p cellular distribution, thus affecting the sphingolipid balance that regulates cell fate. 29496584
2016-04-02 10:57:00 Ceramide signalling impinges on Sit4p and Hog1p to promote mitochondrial fission and mitophagy in Isc1p-deficient cells. 26079297
2012-10-06 10:21:00 The findings supported a role for Hog1p in the regulation of mitochondrial function and suggest that constitutive activation of Hog1p is deleterious for isc1-deficient cells under oxidative stress conditions and during chronological aging. 22445853
2012-02-18 11:08:00 Data show that that ISC1 controls cell morphology in combination with checkpoint regulators Swe1, Cdk1(CDC28), MRC1, TOF1, CSM3, RAD9 and Rad53. 21840863

名称对应

Type IDs
Gene
UniProtKB-ID: ISC1_YEAST
UniprotKB: P40015
UniParc: UPI000012D8CF
EMBL: U18778, BK006939
EnsemblGenome: YER019W
KO: sce:YER019W
Nucleutide sequences
EMBL-CDS: AAB64552.1, DAA07671.1
EnsemblGenome_TRS: YER019W_mRNA
Protein sequencees
EnsemblGenome_PRO: YER019W
RefSeq: NP_010935.1
Others
UniRef100: UniRef100_P40015
UniRef90: UniRef90_P40015
UniRef50: UniRef50_P40015

全选

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