| Type | Description |
|---|---|
| Definition | AAA family ATPase AFG3 |
| Date | Results | Publications |
|---|---|---|
| 2018-01-06 11:46:00 | replacement of the Yta10 TM2 domain abolishes membrane dislocation for only a subset of substrates, whereas replacement of the Yta12 TM2 domain impairs membrane dislocation for all tested substrates, suggesting different roles of the TM domains in each m-AAA protease subunit | 29030426 |
| 2013-10-19 10:17:00 | Observations show a role for the mitochondrial protease Afg3 in modulating cytoplasmic mRNA translation and ER stress resistance, and suggest Afg3 modulates longevity in yeast by a mechanism similar to cytoplasmic ribosomal large subunit proteins. | 23167605 |
| 2011-09-24 12:07:00 | Inactivation of either of the mitochondrial AAA proteases, Yme1 or Yta10/12, allows fermentative growth of hsc82 or hsp82 strains at 37 degrees C. | 21439406 |
| 2010-01-21 00:00:00 | Results describe the localizations of the m-AAA protease, its subunits Yta10 and Yta12, and its substrate cytochrome c peroxidase (Ccp1) within yeast mitochondria. | 19019989 |
| 2010-01-21 00:00:00 | transmembrane segments of m-AAA protease subunits have a direct role in the dislocation of membrane-embedded substrates | 15205678 |
| Type | IDs |
|---|---|
| Synonymous | YTA10 |
| Gene |
UniProtKB-ID:
AFG3_YEAST
UniprotKB:
P39925
UniParc:
UPI0000125663
EMBL:
X81066,
U18778,
X76643,
BK006939
EnsemblGenome:
YER017C
KO:
sce:YER017C
|
| Nucleutide sequences |
EMBL-CDS:
AAB64550.1,
DAA07669.1,
CAA56953.1,
CAA54091.1
EnsemblGenome_TRS:
YER017C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YER017C
RefSeq:
NP_010933.1
|
| Others |
UniRef100:
UniRef100_P39925
UniRef90:
UniRef90_P39925
UniRef50:
UniRef50_P39925
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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