| Type | Description |
|---|---|
| Definition | amino acid starvation-responsive transcription factor GCN4 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 13:04:00 | Genome-scale reconstruction of Gcn4/ATF4 networks driving a growth program. | 33378328 |
| 2020-05-23 10:53:00 | ln4p depletion reduces this sequestration capacity, allowing uncharged tRNAGln to interact with Gcn2 kinase. The study sheds new light on mutant aaRS disease aetiologies, and explains how aaRS sequestration of uncharged tRNAs can prevent GCN4 activation under non-starvation conditions. | 32016368 |
| 2019-10-19 12:21:00 | eIF2beta or eIF1 substitutions disrupting these contacts increase initiation at UUG codons, and compound substitutions also derepress translation of GCN4, indicating slower TC recruitment. | 30576497 |
| 2019-09-21 12:34:00 | Authors find that the large Gcn4-Med15 complex is heterogeneous and contains nearly all possible AD-ABD interactions. Gcn4-Med15 forms via a dynamic fuzzy protein-protein interface, where ADs bind the ABDs in multiple orientations via hydrophobic regions that gain helicity. | 29562181 |
| 2019-07-20 12:52:00 | These findings suggest that Ssb2 is a critical factor that modulates Gcn4 functions in the nucleus and cytosol. | 30039896 |
| Type | IDs |
|---|---|
| Synonymous | AAS101, AAS3, ARG9 |
| Gene |
UniProtKB-ID:
GCN4_YEAST
UniprotKB:
P03069
UniParc:
UPI0000047601
EMBL:
AJ585687,
AJ585689,
AJ585701,
AJ585688,
AJ585686,
AJ585693,
AJ585700,
BK006939,
AJ585699,
AF416613,
AJ585690,
AJ585695,
AJ585692,
AJ585698,
AJ585702,
AJ585697,
K02649,
AJ585691,
U18530,
AJ585703,
K02205,
AJ585696,
AJ585694,
AJ585704
EnsemblGenome:
YEL009C
KO:
sce:YEL009C
|
| Nucleutide sequences |
EMBL-CDS:
CAE52223.1,
CAE52214.1,
CAE52211.1,
CAE52219.1,
CAE52206.1,
CAE52220.1,
CAE52212.1,
CAE52221.1,
CAE52216.1,
CAE52218.1,
AAL09032.1,
CAE52207.1,
AAA34640.1,
CAE52208.1,
CAE52217.1,
CAE52210.1,
CAE52209.1,
CAE52215.1,
AAA65521.1,
CAE52222.1,
AAB64486.1,
DAA07643.1,
CAE52213.1,
CAE52224.1
EnsemblGenome_TRS:
YEL009C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YEL009C
RefSeq:
NP_010907.3
|
| Others |
UniRef100:
UniRef100_P03069
UniRef90:
UniRef90_P03069
UniRef50:
UniRef50_P03069
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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