| Type | Description |
|---|---|
| Definition | protein anchor VAC8 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 11:09:00 | Authors show that Vac8 constitutes a vacuolar tether that stably anchors the PAS to the vacuole throughout autophagosome biogenesis via the PAS component Atg13. S. cerevisiae lacking Vac8 show inefficient autophagosome-vacuole fusion, and form fewer and smaller autophagosomes that often localize away from the vacuole. | 31649143 |
| 2020-01-04 11:31:00 | Study found that non-selective bulk autophagy of cytosolic proteins as well as the selective autophagic degradation of peroxisomes (pexophagy) and ribosomes (ribophagy) was dependent on the armadillo repeat protein Vac8 in Saccharomyces cerevisiae. Moreover, pexophagy and ribophagy depended on the palmitoylation of Vac8. | 31262095 |
| 2018-05-19 10:52:00 | Report the crystal structure of Vac8p bound to Nvj1p at 2.4-A resolution. Vac8p comprises a flexibly connected N-terminal H1 helix followed by 12 armadillo repeats (ARMs) that form a right-handed superhelical structure. The extended 80-A-long loop of Nvj1p specifically binds the highly conserved inner groove formed from ARM1-12 of Vac8p. | 28533415 |
| 2010-01-21 00:00:00 | during vacuole fusion, Nyv1 is the classical R-SNARE, whereas the Ykt6-containing complex has a novel function in Vac8 palmitoylation | 15701652 |
| 2010-01-21 00:00:00 | Data show that each of the three Vac8p putative palmitoylation sites, at Cys 4, 5 and 7, may serve as a palmitoylation site. | 16978392 |
| Type | IDs |
|---|---|
| Synonymous | YEB3 |
| Gene |
UniProtKB-ID:
VAC8_YEAST
UniprotKB:
P39968
UniParc:
UPI00001380B6
EMBL:
AF005267,
U18530,
BK006939
EnsemblGenome:
YEL013W
KO:
sce:YEL013W
|
| Nucleutide sequences |
EMBL-CDS:
DAA07640.1,
AAQ13402.1,
AAB64490.1
EnsemblGenome_TRS:
YEL013W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YEL013W
RefSeq:
NP_010903.3
|
| Others |
UniRef100:
UniRef100_P39968
UniRef90:
UniRef90_P39968
UniRef50:
UniRef50_P39968
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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