| Type | Description |
|---|---|
| Definition | orotidine-5'-phosphate decarboxylase |
| Date | Results | Publications |
|---|---|---|
| 2020-10-03 12:52:00 | Role of the Carboxylate in Enzyme-Catalyzed Decarboxylation of Orotidine 5'-Monophosphate: Stabilization Dominates Over Ground State Destabilization. | 31365243 |
| 2020-01-18 10:11:00 | most of the compensatory mutants were clustered in proximity to the catalytic center | 31058959 |
| 2019-06-01 12:02:00 | Heritable silencing does not impact mutation rate but drives population size expansion and rapid epigenetic adaptation. This eventually leads to genetic assimilation of the silent phenotype by mutations that reduce or abolish URA3 expression. | 30718851 |
| 2017-07-15 12:05:00 | we showed that high levels of copper (previously shown to elevate CUP1 transcription) lead to a substantial elevation in rate of both interhomolog and intra/sister chromatid recombination in the CUP1 array; recombination events that delete the URA3 insertion from the CUP1 array occur at a rate of >10(-3)/division in unselected cells. | 28381587 |
| 2017-06-03 10:50:00 | We found that mutations were scattered throughout the open reading frame of the URA3 gene but clustered to several hotspots with base substitutions/deletions at homo-polymeric runs. Surprisingly, we only detected two multiple mutants out of over 300 sequenced mutation events. | 28419093 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PYRF_YEAST
UniprotKB:
P03962
UniParc:
UPI000004C5DD
EMBL:
U89671,
X00191,
M12926,
BK006939,
U18530,
U89927,
K02207,
U63018,
K02206
EnsemblGenome:
YEL021W
KO:
sce:YEL021W
|
| Nucleutide sequences |
EMBL-CDS:
CAA25010.1,
AAB64383.1,
AAA34824.1,
DAA07631.1,
AAB64498.1,
AAA35199.1,
AAA34825.1,
AAB49978.1,
AAC53678.1
EnsemblGenome_TRS:
YEL021W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YEL021W
RefSeq:
NP_010893.3
|
| Others |
UniRef100:
UniRef100_P03962
UniRef90:
UniRef90_P03962
UniRef50:
UniRef50_P03962
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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