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856677 HYP2

856677

HYP2

translation elongation factor eIF-5A

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition translation elongation factor eIF-5A

研究结论

Date Results Publications
2021-02-06 13:57:00 In vitro yeast reconstituted translation system reveals function of eIF5A for synthesis of long polypeptide. 32053170
2018-12-22 10:43:00 The overexpression of eIF1 improved expression of HIS4(AUG) allele and GCN4 transcript causing 3AT resistance, whereas overexpression of eIF1 resulted in diminished UUG codon recognition of HIS4(UUG) allele causing 3AT sensitivity, despite having higher GCN4 expression 30262708
2017-12-09 12:09:00 the ability of eIF5A from tif51A-4 to bind to the ribosome while potentially blocking physical interaction with P-tRNA could explain its dominant negative phenotype. 27388480
2017-10-28 13:02:00 Data show that translation elongation factor eIF-5A (eIF5A) requirement for polyproline synthesis is imposed by proline, not by tRNAPro. 28637321
2017-10-21 11:59:00 eIF5A facilitates translation termination globally and promotes the elongation of many non polyproline-specific tripeptide sequences. 28549188

名称对应

Type IDs
Synonymous TIF51A
Gene
UniProtKB-ID: IF5A1_YEAST
UniprotKB: P23301
UniParc: UPI00000312E4
EMBL: M63541, BK006939, X56236, D83166, U18779
EnsemblGenome: YEL034W
KO: sce:YEL034W
Nucleutide sequences
EMBL-CDS: DAA07619.1, CAA39693.1, AAA35155.1, BAA11826.1, AAB65008.1
Gene_ORFName: SYGP-ORF21
EnsemblGenome_TRS: YEL034W_mRNA
Protein sequencees
EnsemblGenome_PRO: YEL034W
RefSeq: NP_010880.3
Others
UniRef100: UniRef100_P23301
UniRef90: UniRef90_P23301
UniRef50: UniRef50_P23301

全选

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研究热度

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