| Type | Description |
|---|---|
| Definition | alpha-1,2-mannosidase MNL1 |
| Date | Results | Publications |
|---|---|---|
| 2016-12-17 11:48:00 | Data show that binding of mannosidase Htm1 to protein disulfide isomerase Pdi1 is required for endoplasmic reticulum (ER)-associated protein degradation (ERAD). | 27053108 |
| 2010-09-27 11:56:00 | analysis of an Htm1 (EDEM)-dependent, Mns1-independent Degradation (ERAD) pathway in Saccharomyces cerevisiae | 20511219 |
| 2010-01-21 00:00:00 | Htm1 protein is an alpha1,2-specific exomannosidase that generates the Man(7)GlcNAc(2) oligosaccharide with a terminal alpha1,6-linked mannosyl residue on degradation substrates. | 19124653 |
| 2010-01-21 00:00:00 | This disulfide bond is essential for the ERAD activity of Mnl1p and in turn stabilizes the prolonged association of PDI with Mnl1p | 19279007 |
| 2010-01-21 00:00:00 | Systematic analysis of model substrates revealed that glycans mark structural determinants that are sensitive to the overall folding state of the molecule. | 19458187 |
| Type | IDs |
|---|---|
| Synonymous | HTM1 |
| Gene |
UniProtKB-ID:
MNL1_YEAST
UniprotKB:
P38888
UniParc:
UPI0000052EB0
EMBL:
BK006934,
U00030
EnsemblGenome:
YHR204W
KO:
sce:YHR204W
|
| Nucleutide sequences |
EMBL-CDS:
DAA06897.1,
AAB68370.1
EnsemblGenome_TRS:
YHR204W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YHR204W
RefSeq:
NP_012074.3
|
| Others |
UniRef100:
UniRef100_P38888
UniRef90:
UniRef90_P38888
UniRef50:
UniRef50_P38888
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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