例如:"NBL1", "4681", "drought"
收藏
856607 RPN10

856607

RPN10

proteasome regulatory particle base subunit RPN10

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition proteasome regulatory particle base subunit RPN10

研究结论

Date Results Publications
2018-10-06 10:43:00 Rpn10, but not ubiquitylated-Rpn10, binds Rpn9 in vitro: ubiquitylation functions to dissociate modified ubiquitin receptors from their targets, a function that promotes cyclic activity of ubiquitin receptors 27698474
2017-07-15 11:03:00 Genetic, bioinformatics, biochemical and biophysical data show that attraction between this alpha1-conjugated ubiquitin and the HECT ubiquitin-binding patch pulls the alpha1-helix out of the interface, thereby promoting trimerization. Strikingly, trimerization renders the ubiquitin ligase inactive. 28069708
2016-03-19 10:45:00 functional yeast proteasomes have the capacity to associate and dissociate with Rpn10 and that Rpn10 monoubiquitination decreases the Rpn10-proteasome and Rpn10-Dsk2 associations. 26450923
2015-11-14 11:56:00 Mutations in this disordered region promote ubiquitin chain extension of Rpn10. 26205498
2012-11-24 11:00:00 X-ray analysis revealed that these crystals of Rpn10 belonged to the monoclinic system C2, with unit-cell parameters a = 107.3, b = 49.7, c = 81.3 A, alpha = gamma = 90.0, beta = 130.5 degrees 22949210

名称对应

Type IDs
Synonymous MCB1, SUN1
Gene
UniProtKB-ID: RPN10_YEAST
UniprotKB: P38886
UniParc: UPI0000052E4E
EMBL: AY558289, U00030, D78022, BK006934
EnsemblGenome: YHR200W
KO: sce:YHR200W
Nucleutide sequences
EMBL-CDS: BAA11207.1, AAB68355.1, DAA06893.1, AAS56615.1
EnsemblGenome_TRS: YHR200W_mRNA
Protein sequencees
EnsemblGenome_PRO: YHR200W
RefSeq: NP_012070.3
Others
UniRef100: UniRef100_P38886
UniRef90: UniRef90_P38886
UniRef50: UniRef50_P38886

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员