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856576 ATG7

856576

ATG7

Atg7p

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition Atg7p

研究结论

Date Results Publications
2019-03-23 12:23:00 Atg7 recognizes Atg8 through multiple steps, which would be necessary to induce a conformational change in Atg7 that is optimal for the activation reaction. 29237558
2018-12-22 11:22:00 This study used electron microscopy to measure the size and number of autophagosomes formed with limiting amounts of Atg7 and found them to be both smaller and fewer than normal. This suggests that Atg7 may have an Atg8-independent role in autophagosome initiation in addition to its Atg8-dependent role in autophagosome expansion. 29906462
2013-01-26 10:21:00 The autophagic E2 enzymes Atg3 and Atg10 share the same binding pocket of E1 enzyme Atg7 and provide a framework for understanding the E2 conjugation reaction in autophagy. 22993095
2012-02-04 10:32:00 The structure of the C-terminal domain of Atg7 in complex with Atg8 shows the mode of dimerization and mechanism of recognition of Atg8. 22056771
2011-12-31 10:39:00 Report structural basis of Atg8 activation by a homodimeric E1, Atg7. 22055191

名称对应

Type IDs
Synonymous APG11, APG7, CVT2
Gene
UniProtKB-ID: ATG7_YEAST
UniprotKB: P38862
UniParc: UPI0000125C64
EMBL: AB017925, U00027, BK006934
EnsemblGenome: YHR171W
KO: sce:YHR171W
Nucleutide sequences
EMBL-CDS: AAB68016.1, BAA33474.1, DAA06864.1
EnsemblGenome_TRS: YHR171W_mRNA
Protein sequencees
EnsemblGenome_PRO: YHR171W
RefSeq: NP_012041.1
Others
UniRef100: UniRef100_P38862
UniRef90: UniRef90_P38862
UniRef50: UniRef50_P38862

全选

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研究热度

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