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856536 WSS1

856536

WSS1

metalloendopeptidase WSS1

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition metalloendopeptidase WSS1

研究结论

Date Results Publications
2020-04-18 10:39:00 The yeast proteases Ddi1 and Wss1 are both involved in the DNA replication stress response. 31276951
2017-11-26 00:32:00 e show that SPRTN is a DNA-dependent mammalian protease required for resolving cytotoxic DNA-protein crosslinks (DPCs)- a function that had only been attributed to the metalloprotease Wss1 in budding yeast. We provide genetic evidence that SPRTN and Wss1 function distinctly in vivo to resolve DPCs 27852435
2016-06-11 10:38:00 Upon DNA damage Wss1/Cdc48/Doa1 ternary complex is recruited to sumoylated targets and catalyzes SUMO chain extension through a newly recognized SUMO ligase activity. 26349035
2014-10-25 11:36:00 Data suggest that Wss1 contributes to survival of DNA-protein crosslink (DPC)-harboring cells by acting on DPCs proteolytically. Wss1 enables replication of DPC-containing DNA and thus promotes genome integrity. 24998930
2010-01-21 00:00:00 In dividing cells, Wss1 is exclusively present in the mother cell. 18336552

名称对应

Type IDs
Gene
UniProtKB-ID: WSS1_YEAST
UniprotKB: P38838
UniParc: UPI000013B2D6
EMBL: BK006934, U10398
EnsemblGenome: YHR134W
KO: sce:YHR134W
Nucleutide sequences
EMBL-CDS: DAA06827.1, AAB68404.1
EnsemblGenome_TRS: YHR134W_mRNA
Protein sequencees
EnsemblGenome_PRO: YHR134W
RefSeq: NP_012002.1
Others
UniRef100: UniRef100_P38838
UniRef90: UniRef90_P38838
UniRef50: UniRef50_P38838

全选

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研究热度

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