| Type | Description |
|---|---|
| Definition | transcription factor NDT80 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-02 12:08:00 | Using genetic and biochemical approaches, this work demonstrates that in the presence of DSBs, activated Mek1 binds to Ndt80 and phosphorylates the transcription factor, thus inhibiting DNA binding and preventing Ndt80's function as a transcriptional activator. | 30496175 |
| 2017-07-15 10:17:00 | ndt80 transcription of CDC5 results in degradation of Red1, a meiosis-specific protein required for Mek1 activation, thereby abolishing Mek1 activity completely. Elimination of Mek1 kinase activity allows Rad51-mediated repair of any remaining DSBs. In this way, cells do not enter Meiosis I until recombination is complete and all DSBs are repair | 28249986 |
| 2015-06-27 13:23:00 | The findings suggest that irreversibility of meiotic commitment is a consequence of the NDT80 transcriptional positive feedback loop, which provides the high-level of Ndt80 required for the developmental switch of meiotic commitment. | 24901499 |
| 2012-01-14 10:23:00 | Our results reveal a role for Cdc5 in meiotic checkpoint control by regulating Ndt80 function | 21795394 |
| 2011-10-01 12:08:00 | nuclear localization of Ndt80 is regulated by the pachytene checkpoint through a cytoplasmic anchor mechanism | 21471004 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
NDT80_YEAST
UniprotKB:
P38830
UniParc:
UPI0000168347
EMBL:
BK006934,
U10398,
U35122,
AY723825
EnsemblGenome:
YHR124W
KO:
sce:YHR124W
|
| Nucleutide sequences |
EMBL-CDS:
AAB68408.1,
AAU09742.1,
DAA06818.1,
AAA92299.1
EnsemblGenome_TRS:
YHR124W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YHR124W
RefSeq:
NP_011992.1
|
| Others |
UniRef100:
UniRef100_P38830
UniRef90:
UniRef90_P38830
UniRef50:
UniRef50_P38830
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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