| Type | Description |
|---|---|
| Definition | origin recognition complex subunit 6 |
| Date | Results | Publications |
|---|---|---|
| 2011-04-30 10:23:00 | The Orc6 RXL/cyclin-binding motif plays a positive role in the initial recruitment of Cdt1/Mcm2-7 to the origin, suggesting that this motif is critical for the switch between active and inhibited ORC function at the G1-to-S-phase transition. | 21289063 |
| 2010-01-21 00:00:00 | Orc6 was required for entry into S phase after pre-replicative complexes formation | 17053779 |
| 2010-01-21 00:00:00 | In this study, yeast two-hybrid analysis was used to examine the interaction between Cdt1p and every ORC subunit; potent interaction with Orc6p, and weaker interaction with Orc2p and Orc5p was observed. | 17825064 |
| 2010-01-21 00:00:00 | The 'hydrophobic patch' (HP) of the Saccharomyces cerevisiae S-phase cyclin Clb5 facilitates its interaction with Orc6 (via its Cy or RXL motif), providing a mechanism that helps prevent rereplication from individual origins. | 15611618 |
| 2010-01-21 00:00:00 | Orc6 is required for dynamic recruitment of Cdt1 during repeated loading of DNA helicases. | 18006685 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
ORC6_YEAST
UniprotKB:
P38826
UniParc:
UPI0000130E65
EMBL:
U00059,
BK006934,
L23323
EnsemblGenome:
YHR118C
KO:
sce:YHR118C
|
| Nucleutide sequences |
EMBL-CDS:
AAB68869.1,
DAA06812.1,
AAA21822.1
EnsemblGenome_TRS:
YHR118C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YHR118C
RefSeq:
NP_011986.1
|
| Others |
UniRef100:
UniRef100_P38826
UniRef90:
UniRef90_P38826
UniRef50:
UniRef50_P38826
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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