| Type | Description |
|---|---|
| Definition | tyrosyl-tRNA synthetase |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:00:00 | Moonlighting matrix metalloproteinase substrates: Enhancement of proinflammatory functions of extracellular tyrosyl-tRNA synthetase upon cleavage. | 31771979 |
| 2020-05-23 11:50:00 | study revealed a new radiation protection mechanism for RSV, in which the acetylation of TyrRS and its translocation into the nucleus is promoted, and this mechanism may also represent a novel protective target against irradiation. | 30939244 |
| 2020-02-29 11:10:00 | By revealing the existence of a YARS-PI3K-Akt signaling axis in gastric cancer, we discovered that tRNA synthetase YARS is a novel tumorigenic factor, characterized by its upregulation in tumor-derived specimens, as well as its functions in promoting gastric cancer progression. | 31912229 |
| 2019-06-22 10:34:00 | Analysis of YARS p.Pro167Thr in yeast complementation assays revealed a loss-of-function, hypomorphic allele that significantly impaired growth. Recombinant YARS p.Pro167Thr demonstrated normal subcellular localization, but greatly diminished ability to homodimerize in human embryonic kidney cells. | 30304524 |
| 2018-12-29 10:19:00 | conclusion is further supported by a positive correlation across brain regions between TyrRS expression and arginine-accelerated KTP production. | 29289698 |
| Type | IDs |
|---|---|
| Synonymous | CMTDIC, TYRRS, YRS, YTS |
| Gene |
UniProtKB-ID:
SYYC_HUMAN,
A0A0S2Z4R1_HUMAN
UniprotKB:
P54577,
A0A0S2Z4R1
UniParc:
UPI0000136762
EMBL:
U89436,
AK125213,
KU178431,
CH471059,
BC004151,
BC001933,
AK223608,
BC016689,
U40714
Ensembl:
ENSG00000134684
KO:
hsa:8565
|
| Nucleutide sequences |
EMBL-CDS:
BAG54166.1,
BAD97328.1,
AAH16689.1,
AAH04151.1,
AAH01933.1,
AAB88409.1,
EAX07506.1,
AAB39406.1,
EAX07507.1,
ALQ33889.1
Ensembl_TRS:
ENST00000373477
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000362576
RefSeq:
XP_016858140.1,
XP_011540650.1,
XP_011540649.1,
NP_003671.1
|
| Others |
UniRef100:
UniRef100_P54577
UniRef90:
UniRef90_P54577
UniRef50:
UniRef50_P54577
UniGene:
Hs.213264
CCDS:
CCDS368.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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