| Type | Description |
|---|---|
| Definition | bifunctional endoribonuclease/protein kinase IRE1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:26:00 | Stress sensor Ire1 deploys a divergent transcriptional program in response to lipid bilayer stress. | 32349127 |
| 2020-06-06 10:47:00 | Unfolded protein response (UPR) is subject to inhibition by oxidative stress. Inhibition is mediated by a single evolutionarily conserved cysteine in Ire1, and affects both luminal and membrane pathways of Ire1 activation. | 31002390 |
| 2019-07-06 11:18:00 | Endoplasmic reticulum stress causes a diminished mRNA decay, thus resulting in the production of a population with an increased abundance of pre-HAC1 mRNA carrying an intact bipartite element, which facilitates its more efficient recruitment to Ire1p foci. | 29165698 |
| 2017-09-30 12:03:00 | The most conserved transducer of ER stress, Ire1, uses an amphipathic helix to sense membrane aberrancies and control unfolded protein response activity. | 28689662 |
| 2015-07-04 12:12:00 | the AMPK Snf1p and ER stress kinase Ire1p regulated the HOG pathway. | 25356552 |
| Type | IDs |
|---|---|
| Synonymous | ERN1 |
| Gene |
UniProtKB-ID:
IRE1_YEAST
UniprotKB:
P32361
UniParc:
UPI000012D881
EMBL:
L19640,
U10556,
BK006934,
Z11701
EnsemblGenome:
YHR079C
KO:
sce:YHR079C
|
| Nucleutide sequences |
EMBL-CDS:
AAA34489.1,
AAB68894.1,
CAA77763.1,
DAA06773.1
EnsemblGenome_TRS:
YHR079C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YHR079C
RefSeq:
NP_011946.1
|
| Others |
UniRef100:
UniRef100_P32361
UniRef90:
UniRef90_P32361
UniRef50:
UniRef50_P32361
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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