| Type | Description |
|---|---|
| Definition | Gic1p |
| Date | Results | Publications |
|---|---|---|
| 2019-04-27 10:27:00 | In yeast cells, Cdc42 polarization involves a positive feedback loop in which effectors called p21-activated kinases (PAKs) act to recruit a Cdc42-directed guanine nucleotide exchange factor (GEF), generating more GTP-Cdc42 in areas that already have GTP-Cdc42. The GTPase-interacting components (GICs) Gic1 and Gic2 are also Cdc42 effectors, and have been implicated in regulation of the actin and septin cytoskeleton. | 30566437 |
| 2017-02-18 12:12:00 | we performed domain analysis to identify domain(s) of Gic1 that are important for its boundary activity, and identified two minimum domains, which are located outside its Cdc42-binding domain. | 27301280 |
| 2015-03-07 11:02:00 | we have used electron microscopy and cryo electron tomography to elucidate the structural basis of the Gic1-septin and Gic1-Cdc42-septin interaction | 24286829 |
| 2010-01-21 00:00:00 | High-copy GIC1 suppresses the growth defect of a mutant (stt1), suggesting the existence of a Pkc1-Zds1-Gic1 pathway. | 16157662 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
GIC1_YEAST
UniprotKB:
P38785
UniParc:
UPI000012B42D
EMBL:
U00061,
BK006934
EnsemblGenome:
YHR061C
KO:
sce:YHR061C
|
| Nucleutide sequences |
EMBL-CDS:
AAB68388.1,
DAA06754.1
EnsemblGenome_TRS:
YHR061C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YHR061C
RefSeq:
NP_011928.1
|
| Others |
UniRef100:
UniRef100_P38785
UniRef90:
UniRef90_P38785
UniRef50:
UniRef50_P38785
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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