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856422 RPN1

856422

RPN1

proteasome regulatory particle base subunit RPN1

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition proteasome regulatory particle base subunit RPN1

研究结论

Date Results Publications
2017-10-07 11:58:00 The structures of proteasome substrate receptor complexes with the shuttle factors that deliver ubiquitinated proteins to proteasomes have been solved, namely human Rpn13 complexed with PLIC2 and Saccharomyces cerevisiae Rpn1 with Rad23. 27396824
2016-07-16 11:01:00 Data suggest regulated process for removal of proteasomes upon nitrogen starvation; autophagy involves separate processes for dissociation and nuclear export of core (PRE2) and regulatory (RPN1) proteins; only core protein autophagy depends on UBP3. 26670610
2016-03-12 11:04:00 Study found that the five known proteasomal ubiquitin receptors in yeast are collectively nonessential for ubiquitin recognition and identified a sixth receptor, Rpn1. A site (T1:) in the Rpn1 toroid recognized ubiquitin and ubiquitin-like (UBL:) domains of substrate shuttling factors. 26912900
2012-07-07 10:51:00 Rpn1 and Rpn2 coordinate ubiquitin processing factors at proteasome. 22318722
2011-10-01 12:07:00 The current study identifies residues in the LRR1 domain of Rpn1 that contribute to shuttle receptor docking. It validates Ddi1 as a proteasomal shuttle receptor whose stable binding to the proteasome depends on Rpn1 residue D517. 21627799

名称对应

Type IDs
Synonymous HRD2, NAS1
Gene
UniProtKB-ID: RPN1_YEAST
UniprotKB: P38764
UniParc: UPI0000134646
EMBL: U10399, BK006934
EnsemblGenome: YHR027C
KO: sce:YHR027C
Nucleutide sequences
EMBL-CDS: AAB68878.1, DAA06718.1
EnsemblGenome_TRS: YHR027C_mRNA
Protein sequencees
EnsemblGenome_PRO: YHR027C
RefSeq: NP_011892.1
Others
UniRef100: UniRef100_P38764
UniRef90: UniRef90_P38764
UniRef50: UniRef50_P38764

全选

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研究热度

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