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856241 CTR1

856241

CTR1

high-affinity Cu transporter CTR1

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition high-affinity Cu transporter CTR1

研究结论

Date Results Publications
2021-03-13 13:17:00 EGCG regulates CTR1 expression through its pro-oxidative property in non-small-cell lung cancer cells. 31943177
2020-03-21 11:37:00 IGF1R prognosticates prolonged survival in HGSOC patients, possibly due to its positive correlation with hCtr1 31140856
2019-05-18 10:57:00 Rho0 cells demonstrated loss of Sco1, resulting in copper deficiency by lowering copper transporter 1 abundance, via mechanism involving increased turnover due to ubiquitination. These findings reveal that a Sco1-dependent mitochondrial signal regulates cellular cisplatin import and cytotoxicity. 30041154
2019-02-23 11:59:00 Expression of the human copper transporter 1 in SOD1G37R transgenic ALS mice increases copper levels in the spinal cord and restores SOD1 activity. 29906423
2018-07-21 12:10:00 Several biological properties of the GST-hNdCTR1 fusion protein were assessed. It was demonstrated that in cells, the protein was prone to oligomerization, formed inclusion bodies and displayed no toxicity. Treatment of E. coli cells with copper and silver ions reduced cell viability in a dose- and time-dependent manner 29099786

名称对应

Type IDs
Gene
UniProtKB-ID: CTR1_YEAST
UniprotKB: P49573
UniParc: UPI0000128656
EMBL: U02511, AY693062, U40828, BK006949
EnsemblGenome: YPR124W
KO: sce:YPR124W
Nucleutide sequences
EMBL-CDS: AAA17369.1, AAB68064.1, DAA11538.1, AAT93081.1
Gene_ORFName: P9642.3
EnsemblGenome_TRS: YPR124W_mRNA
Protein sequencees
EnsemblGenome_PRO: YPR124W
RefSeq: NP_015449.1
Others
UniRef100: UniRef100_P49573
UniRef90: UniRef90_P49573
UniRef50: UniRef50_P49573

全选

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研究热度

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