| Type | Description |
|---|---|
| Definition | high-mobility group nucleosome-binding protein |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:23:00 | The HMGB chromatin protein Nhp6A can bypass obstacles when traveling on DNA. | 32997109 |
| 2020-07-11 10:28:00 | he absence of chromatin regulators like Nhp6 A and B, interferes with a regulative circular mechanism where histone modification, transcription and metabolism influence each other and contribute to clarify the more general phenomenon in which gene regulation feeds metabolic alterations on epigenetic basis. | 31676292 |
| 2019-11-16 11:53:00 | First direct observation of bending/unbending dynamics of DNA in complex with yNhp6A, suggesting a bind-then-bend mechanism for this protein. | 30698746 |
| 2017-11-04 11:33:00 | Nhp6 proteins, the HMGB1 homologues, control histone gene expression by affecting nucleosome stability at regulative regions of the histone clusters. In addition, we observe that histone gene overexpression in the nhp6ab mutant is accompanied by downregulated translation, which in turn is responsible for the histone decrease phenotype. | 28025045 |
| 2017-08-19 11:22:00 | studied the genome-wide binding patterns of Nhp6, Hmo1 and the SWI/SNF complex, finding that most of gene promoters presenting high occupancy of this complex also display high enrichment of these HMG proteins. | 28089519 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
NHP6A_YEAST
UniprotKB:
P11632
UniParc:
UPI0000110C5D
EMBL:
Z49219,
AY693230,
M95912,
BK006949,
X15317,
Z71255
EnsemblGenome:
YPR052C
KO:
sce:YPR052C
|
| Nucleutide sequences |
EMBL-CDS:
CAA33377.1,
DAA11475.1,
CAA89171.1,
AAA34754.1,
AAT93249.1,
CAA94998.1
Gene_ORFName:
YP9499.09C
EnsemblGenome_TRS:
YPR052C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YPR052C
RefSeq:
NP_015377.1
|
| Others |
UniRef100:
UniRef100_P11632
UniRef90:
UniRef90_P11632
UniRef50:
UniRef50_P11632
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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