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856154 TIF5

856154

TIF5

translation initiation factor eIF5

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition translation initiation factor eIF5

研究结论

Date Results Publications
2019-03-30 12:29:00 Substitutions of eIF5 residues involved in the interaction influenced initiation at near-cognate UUG codonsin vivo, and the closed/open PIC conformation in vitro, consistent with direct stabilization of the codon:anticodon duplex by the wild-type eIF5-NTD. 30475211
2018-01-13 14:14:00 These data uncover competition between eIF2B and eIF5 for ternary complexes and identify that phosphorylated eIF2-GTP translation initiation intermediate complexes can be inhibited by eIF2B. 28315520
2014-03-08 10:40:00 eIF5-CTD (amino acids 241-405; Tif5p-B6) interacted with eIF1A (Tif11p). 24319994
2014-02-08 11:23:00 eIF2B has a second activity as a GDI displacement factor (GDF) that can recruit eIF2 from the eIF2*GDP/eIF5 GDI complex prior to GEF action. 24352424
2010-01-21 00:00:00 The direct interaction at eIF1 places eIF5 near the decoding site of the 40 S subunit. 17974565

名称对应

Type IDs
Synonymous SUI5
Gene
UniProtKB-ID: IF5_YEAST
UniprotKB: P38431
UniParc: UPI0000053148, UPI0000D7A4B1
EMBL: Z73616, Z68111, BK006949, L10840, Z71255
EnsemblGenome: YPR041W
KO: sce:YPR041W
Nucleutide sequences
EMBL-CDS: CAA94989.1, CAA97991.1, CAA92145.1, DAA11466.1
Gene_ORFName: YP3085.05
EnsemblGenome_TRS: YPR041W_mRNA
Protein sequencees
EnsemblGenome_PRO: YPR041W
RefSeq: NP_015366.1
Others
UniRef100: UniRef100_P38431
UniRef90: UniRef90_P38431
UniRef50: UniRef50_P38431

全选

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研究热度

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