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856134 EAF3

856134

EAF3

Eaf3p

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition Eaf3p

研究结论

Date Results Publications
2021-03-20 13:23:00 The Eaf3 chromodomain acts as a pH sensor for gene expression by altering its binding affinity for histone methylated-lysine residues. 32031206
2020-08-01 10:10:00 Eaf3 is recruited to intron-containing genes and that Eaf3 interacts with the splicing factor Prp45. Eaf3 acts with Prp45 and Prp19 after formation of the precatalytic B complex around the time of splicing activation, thus revealing the step in splicing that is regulated by H3K36 methylation. 31242410
2017-06-24 10:28:00 Results demonstrate that the combination of Eaf3 and Yng2 interactions with their respective methyl marks on histone H3 is not important for NuA4 localization on the genome but is required for proper H4 acetylation throughout the transcription unit. 27550811
2017-05-20 12:46:00 In vitro binding assays showed that Eaf3/5/7 specifically stimulates NuA4 binding to di- and trimethylated histone H3 Lys-36 and that this binding is important for NuA4 occupancy in transcribed ORFs. 27535225
2010-01-21 00:00:00 The association of Rpd3S with chromatin requires its Eaf3 subunit, which binds histone H3 methylated at lysine 36. 18818090

名称对应

Type IDs
Gene
UniProtKB-ID: EAF3_YEAST
UniprotKB: Q12432
UniParc: UPI0000052F18
EMBL: BK006949, Z49274, Z71255
EnsemblGenome: YPR023C
KO: sce:YPR023C
Nucleutide sequences
EMBL-CDS: DAA11449.1, CAA95019.1, CAA89277.1
Gene_ORFName: YP9367.03C
EnsemblGenome_TRS: YPR023C_mRNA
Protein sequencees
EnsemblGenome_PRO: YPR023C
RefSeq: NP_015348.1
Others
UniRef100: UniRef100_Q12432
UniRef90: UniRef90_Q12432
UniRef50: UniRef50_Q12432

全选

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研究热度

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