| Type | Description |
|---|---|
| Definition | MCM DNA helicase complex subunit MCM4 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-08 12:06:00 | The authors identified mutations in a conserved and essential Mcm4 motif that permit loading of two Mcm2-7 complexes but are defective for double-hexamer formation. | 31385807 |
| 2017-07-08 10:49:00 | Sld3 binds specifically to DDK-phosphorylated peptides from two MCM subunits (Mcm4, 6) and then recruits Cdc45. | 26912723 |
| 2014-07-05 10:17:00 | The Dbf4-dependent Cdc7 kinase (DDK), cyclin-dependent kinase (CDK), and Mec1 all target the structurally disordered N-terminal serine/threonine-rich domain of Mcm4, a subunit of the mini-chromosome maintenance replicative helicase complex. | 24740181 |
| 2013-08-10 10:36:00 | constitutive overexpression of each individual MCM subunit was examined, and genotoxic sensitivity was found to be specific to Mcm2 or Mcm4 overexpression, further pointing to the importance of the DDK-MCM ring interaction. | 23549044 |
| 2011-08-20 10:58:00 | A defective MCM helicase causes genetic instability only in particular cell types. | 21242538 |
| Type | IDs |
|---|---|
| Synonymous | CDC54, HCD21 |
| Gene |
UniProtKB-ID:
MCM4_YEAST
UniprotKB:
P30665
UniParc:
UPI0000127256
EMBL:
Z71255,
Z15032,
U14731,
BK006949,
Z49919
EnsemblGenome:
YPR019W
KO:
sce:YPR019W
|
| Nucleutide sequences |
EMBL-CDS:
AAA86310.1,
DAA11445.1,
CAA78750.1,
CAA90164.1,
CAA95015.1
Gene_ORFName:
YP9531.13
EnsemblGenome_TRS:
YPR019W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YPR019W
RefSeq:
NP_015344.1
|
| Others |
UniRef100:
UniRef100_P30665
UniRef90:
UniRef90_P30665
UniRef50:
UniRef50_P30665
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员