| Type | Description |
|---|---|
| Definition | histone deacetylase HST2 |
| Date | Results | Publications |
|---|---|---|
| 2012-07-14 11:23:00 | Data show that Sir2, and not Hst2, regulates the acetylation state of H3 lysine 79. | 22474337 |
| 2010-01-21 00:00:00 | Here, we show that Hst2 moves between the nucleus and cytoplasm, but is largely cytoplasmic owing to efficient nuclear export.Disruption of Hst2 export shows that nuclear exclusion inhibits the activity of Hst2 as a transcriptional repressor. | 17110954 |
| 2010-01-21 00:00:00 | Specific functions were found for HST2. | 17446861 |
| 2010-01-21 00:00:00 | results show that HST2 is responsible for Sir2-independent life-span extension by calorie restriction and that it does so by suppressing rDNA recombination, the same mechanism by which SIR2 extends life span | 16051752 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
HST2_YEAST
UniprotKB:
P53686
UniParc:
UPI000012CDAB
EMBL:
U33335,
AY693204,
U39063,
BK006949
EnsemblGenome:
YPL015C
KO:
sce:YPL015C
|
| Nucleutide sequences |
EMBL-CDS:
AAB68090.1,
AAA81035.1,
DAA11413.1,
AAT93223.1
Gene_ORFName:
LPA2C
EnsemblGenome_TRS:
YPL015C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YPL015C
RefSeq:
NP_015310.1
|
| Others |
UniRef100:
UniRef100_P53686
UniRef90:
UniRef90_P53686
UniRef50:
UniRef50_P53686
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 29674565 |
Systematic analysis of complex genetic interactions. Science Elena Kuzmin , Benjamin VanderSluis , Wen Wang , Guihong Tan , Raamesh Deshpande , Yiqun Chen , Matej Usaj , Attila Balint , Mojca Mattiazzi Usaj , Jolanda van Leeuwen , Elizabeth N Koch , Carles Pons , Andrius J Dagilis , Michael Pryszlak , Jason Zi Yang Wang , Julia Hanchard , Margot Riggi , Kaicong Xu , Hamed Heydari , Bryan-Joseph San Luis , Ermira Shuteriqi , Hongwei Zhu , Nydia Van Dyk , Sara Sharifpoor , Michael Costanzo , Robbie Loewith , Amy Caudy , Daniel Bolnick , Grant W Brown , Brenda J Andrews , Charles Boone , Chad L Myers |
2018-04-20 | - |
| 29158339 |
G3 (Bethesda) Jason E Miller , Liye Zhang , Haoyang Jiang , Yunfei Li , B Franklin Pugh , Joseph C Reese |
2018-01-04 | - |
| 27708008 |
A global genetic interaction network maps a wiring diagram of cellular function. Science Michael Costanzo , Benjamin VanderSluis , Elizabeth N Koch , Anastasia Baryshnikova , Carles Pons , Guihong Tan , Wen Wang , Matej Usaj , Julia Hanchard , Susan D Lee , Vicent Pelechano , Erin B Styles , Maximilian Billmann , Jolanda van Leeuwen , Nydia van Dyk , Zhen-Yuan Lin , Elena Kuzmin , Justin Nelson , Jeff S Piotrowski , Tharan Srikumar , Sondra Bahr , Yiqun Chen , Raamesh Deshpande , Christoph F Kurat , Sheena C Li , Zhijian Li , Mojca Mattiazzi Usaj , Hiroki Okada , Natasha Pascoe , Bryan-Joseph San Luis , Sara Sharifpoor , Emira Shuteriqi , Scott W Simpkins , Jamie Snider , Harsha Garadi Suresh , Yizhao Tan , Hongwei Zhu , Noel Malod-Dognin , Vuk Janjic , Natasa Przulj , Olga G Troyanskaya , Igor Stagljar , Tian Xia , Yoshikazu Ohya , Anne-Claude Gingras , Brian Raught , Michael Boutros , Lars M Steinmetz , Claire L Moore , Adam P Rosebrock , Amy A Caudy , Chad L Myers , Brenda Andrews , Charles Boone |
2016-09-23 | - |
| 25381059 |
Mol Cell Proteomics Michael Downey , Jeffrey R Johnson , Norman E Davey , Billy W Newton , Tasha L Johnson , Shastyn Galaang , Charles A Seller , Nevan Krogan , David P Toczyski |
2015-01-01 | - |
| 26673895 |
A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Elife Koray Kırlı , Samir Karaca , Heinz Jürgen Dehne , Matthias Samwer , Kuan Ting Pan , Christof Lenz , Henning Urlaub , Dirk Görlich |
2015-01-01 |
CHA1,
KRR1,
SRO9,
STE50,
RRP7,
RNQ1,
DCC1,
GBP2,
SAT4,
RVS161,
YCR016W,
PWP2,
SSK22,
SOL2,
PAT1,
YCR087C-A,
OCA4,
MOB2,
EPL1,
BUD27,
FRS2,
LOC1,
YFR016C,
LSB3,
RPL2A,
PHO4,
SAP155,
IRC6,
ENT4,
PRP19,
RIX7,
YLL032C,
FRA1,
ISA1,
SPA2,
PUF3,
RPL8B,
NOC3,
SSL1,
SSK1,
NSE1,
RLP24,
SDO1,
ADE16,
RPL15A,
STU2,
RPS0B,
FRS1,
BMT6,
KIN2,
HRT3,
REX3,
YLR108C,
CFT2,
MSL5,
ACE2,
STM1,
YLR157C-A,
APS1,
CBF5,
SWI6,
SKG3,
HCR1,
PWP1,
NOP56,
BUR2,
GPN3,
DBP9,
GCD7,
SGD1,
STE11,
NMD4,
RPS22B,
ROM2,
STP3,
IKI3,
REH1,
AFG2,
UTP21,
ATG17,
TUS1,
MAG2,
ATG23,
RPS1A,
FPR4,
PDP3,
CDC24,
RBG1,
FUN12,
MTW1,
PRP45,
MAK16,
ECM1,
GPB2,
VPS8,
KIN3,
CDC15,
YAT1,
WHI4
|
| 23332755 |
The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis. Cell Felix Willmund , Marta del Alamo , Sebastian Pechmann , Taotao Chen , Véronique Albanèse , Eric B Dammer , Junmin Peng , Judith Frydman |
2013-01-17 |
VAC17,
MIC10,
PRD1,
KAR4,
PBN1,
APA1,
POF1,
MGR1,
GLK1,
SRO9,
GFD2,
GRX1,
LSB5,
RNQ1,
HBN1,
DCC1,
GBP2,
ILV6,
STP22,
CDC10,
YCP4,
CIT2,
RVS161,
PGK1,
RHB1,
RIM1,
SYP1,
RPS14A,
RRP43,
YCR043C,
YCR051W,
THR4,
CTR86,
PWP2,
YIH1,
TAH1,
HCM1,
RSA4,
SOL2,
FUB1,
PAT1,
AHC2,
TRX3,
TUP1,
CSM1,
YCR090C,
MSH3,
YCR102C,
SNZ3,
SWP82,
RGD2,
SEC53,
OTU1,
ACT1,
YPT1,
TUB2,
MOB2,
RPL22B,
HAC1,
CAF16,
FRS2,
GAT1,
LPD1,
BLM10,
SEC4,
VTC2,
SPB4,
RPN11,
YFR006W,
YFH7,
IOC3,
ATG18,
LSB3,
HIS2,
CDC14,
RPL2A,
DUG1,
BNA6,
RMD8,
YMR31,
PRE4,
RET2,
RPN12,
HXK1,
IRC7,
GRC3,
RIX7,
YLL032C,
FRA1,
ISA1,
HSP104,
SSA2,
HIF1,
DPS1,
LMO1,
ORC3,
RTT109,
MHT1,
YLL058W
|
| 22689984 |
Cdc28 kinase activity regulates the basal transcription machinery at a subset of genes. Proc. Natl. Acad. Sci. U.S.A. Pierre Chymkowitch , Vegard Eldholm , Susanne Lorenz , Christine Zimmermann , Jessica M Lindvall , Magnar Bjørås , Leonardo A Meza-Zepeda , Jorrit M Enserink |
2012-06-26 |
suc1,
RAD18,
RTT109,
RAD5,
RFX1,
BUR2,
RSC2,
IKI3,
CDC73,
SIR3,
CCR4,
RPO21,
KIN28,
BRE1,
SIR2,
RPN4,
NHP10,
SIR4,
DOT1,
SDC1,
HIR1,
CDC28,
ABD1,
ISW1,
RTF1,
CEG1,
MMS2,
RAD6,
DST1,
SPT4,
UBR1,
NAS6,
GCN5,
SET2,
ASF1,
ESS1,
CTK1,
DEF1,
NAP1,
SIR1,
PAP2,
HTZ1,
HIR2,
LEO1,
ARP8,
UBP8,
FCP1,
RPD3,
SSU72,
HDA1,
TAF14,
HHO1,
ELP4,
LGE1,
HST2,
HOS1,
SET1,
RPN10,
MOT2,
RTR1,
CHD1,
CDK1
|
| 22474337 |
Proc. Natl. Acad. Sci. U.S.A. Poonam Bheda , Stephen Swatkoski , Katherine L Fiedler , Jef D Boeke , Robert J Cotter , Cynthia Wolberger |
2012-04-17 |
SIR2,
HHT1,
HHT2,
HST2
|
| 22271760 |
La-motif-dependent mRNA association with Slf1 promotes copper detoxification in yeast. RNA Luca Schenk , Dominik M Meinel , Katja Strässer , André P Gerber |
2012-03-01 |
YLR361C-A,
YDR003W-A,
SUS1,
YGR204C-A,
YJR112W-A,
YOR020W-A,
YIL002W-A,
YNL067W-B,
COA2,
YHL048C-A,
YHR175W-A,
PCC1,
VMA9,
MIC10,
PRD1,
PBN1,
SRO9,
GRX1,
LSB5,
MXR2,
STE50,
HIS4,
ILV6,
RER1,
MRPL32,
RVS161,
MAK31,
PMP1,
RHB1,
RIM1,
RPS14A,
RRP43,
YCR043C,
PER1,
BUD23,
ARE1,
YCR051W,
TAH1,
IMG2,
SSK22,
SOL2,
FUB1,
AHC2,
TRX3,
ABP1,
YCR090C,
HMRA1,
FMP32,
YPT1,
RPL22B,
GNA1,
HSP12,
WWM1,
LOC1,
YPI1,
IGD1,
HIS2,
RPL2A,
RPL29,
RSC8,
ERJ5,
KEG1,
DUG1,
YMR31,
EMC6,
COX17,
COF1,
LDB18,
RPL8B,
PAM18,
LOT6,
MEU1,
SED5,
RPL15A,
COX12,
IES3,
SPT8,
SHM2,
REX2,
ENV10,
SPC3,
FMP25,
ERG27,
SEN2,
AHP1,
SRN2,
YPS3,
DCN1,
ZRT2,
USB1,
RMP1,
SMD3,
RNH203,
ASP3-2,
RPS31,
UPS2,
DPH5,
TFS1,
YLR179C
|
| 21742760 |
Histone modifications influence mediator interactions with chromatin. Nucleic Acids Res Xuefeng Zhu , Yongqiang Zhang , Gudrun Bjornsdottir , Zhongle Liu , Amy Quan , Michael Costanzo , Marcela Dávila López , Jakub Orzechowski Westholm , Hans Ronne , Charles Boone , Claes M Gustafsson , Lawrence C Myers |
2011-10-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员