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856085 RAD1

856085

RAD1

ssDNA endodeoxyribonuclease RAD1

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition ssDNA endodeoxyribonuclease RAD1

研究结论

Date Results Publications
2019-08-24 10:04:00 RAD1 interactions with RAD10, Msh2-Msh3 and RPA is necessary for 3' non-homologous tail removal. 29660012
2018-12-22 10:28:00 Rad1-Rad10 makes distinct contributions to inter-strand crosslink repair (ICLR) depending on cell cycle phase: in G1, Rad1-Rad10 removes ICL via non-nucleotide excision repair (NER), whereas in S/G2, Rad1-Rad10 facilitates NER-independent replication-coupled. Results suggest that NER function in ICLR is conserved from yeast to human and yeast will provide a tractable system to dissect this critical repair pathway. 29795289
2018-04-21 11:29:00 One example occurred when yeast lacking RAD1 were exposed to cisplatin, and we characterized this interaction using whole-genome sequencing. Our sequencing results indicate mutagenesis by cisplatin in rad1Delta cells appeared to depend almost entirely on interstrand cross-links at GpCpN motifs. 28223526
2012-11-17 10:24:00 Presented is a model for the role of Rad1-Rad10 cleavage in formation of recombinants between dispersed repeats. 22885325
2010-04-19 11:22:00 low frequency of translocations observed in rad1-null single mutants 20012294

名称对应

Type IDs
Synonymous LPB9, RAD12
Gene
UniProtKB-ID: RAD1_YEAST
UniprotKB: P06777
UniParc: UPI0000052FC5
EMBL: BK006949, U36624, K02070, M15435
EnsemblGenome: YPL022W
KO: sce:YPL022W
Nucleutide sequences
EMBL-CDS: AAB68165.1, DAA11406.1, AAA34929.1, AAA34934.1
EnsemblGenome_TRS: YPL022W_mRNA
Protein sequencees
EnsemblGenome_PRO: YPL022W
RefSeq: NP_015303.1
Others
UniRef100: UniRef100_P06777
UniRef90: UniRef90_P06777
UniRef50: UniRef50_P06777

全选

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研究热度

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