| Type | Description |
|---|---|
| Definition | cyclin-dependent serine/threonine-protein kinase PHO85 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:11:00 | Cyclin-dependent kinase Pho85p and its cyclins are involved in replicative lifespan through multiple pathways in yeast. | 31797348 |
| 2020-05-16 11:09:00 | Study results provide evidence that phosphatidylinositol 4,5-bisphosphate modulates the activity of essential signaling effectors in response to cold and that Pho85 is a central regulator of lipid homeostasis in yeast Saccharomyces cerevisiae. Its activity connects different lipid biosynthesis pathways to endow yeast cells with the optimal lipid profile to face with thermal stress. | 31678512 |
| 2017-09-16 11:52:00 | Pho85/CDK5 provides protection against hyperosmotic stress and acts before long-term adaptation provided by Hog1. This protection requires the vacuolar/endolysosomal signaling lipid PI3,5P2 We show that Pho85/CDK5 directly phosphorylates and positively regulates the PI3P-5 kinase Fab1/PIKfyve complex and provide evidence that this regulation is conserved in mammalian cells. | 28637746 |
| 2015-10-31 10:33:00 | Pho85 and Pho4 regulated CLN2 expression under alkaline condition. | 25582350 |
| 2015-02-14 14:07:00 | with Srb10 clearing mostly inactive Gcn4 molecules at the promoter that are enriched for sumoylation of the activation domain, and Pho85 clearing molecules unbound to the UAS that include both fully functional and inactive Gcn4 species. | 25079372 |
| Type | IDs |
|---|---|
| Synonymous | LDB15 |
| Gene |
UniProtKB-ID:
PHO85_YEAST
UniprotKB:
P17157
UniParc:
UPI00001318AE
EMBL:
BK006949,
U44030,
Y00867
EnsemblGenome:
YPL031C
KO:
sce:YPL031C
|
| Nucleutide sequences |
EMBL-CDS:
DAA11398.1,
CAA68774.1,
AAB68188.1,
CAA68773.1
Gene_ORFName:
P7102.18A
EnsemblGenome_TRS:
YPL031C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YPL031C
RefSeq:
NP_015294.1
|
| Others |
UniRef100:
UniRef100_P17157
UniRef90:
UniRef90_P17157
UniRef50:
UniRef50_P17157
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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