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856065 SSN3

856065

SSN3

cyclin-dependent serine/threonine protein kinase SSN3

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition cyclin-dependent serine/threonine protein kinase SSN3

研究结论

Date Results Publications
2020-06-13 11:52:00 CDK8 could overcome the transcriptional and posttranscriptional alterations of the fcp1 mutant by increasing Skn7 stability, protein levels, and likely the expression of target genes. 31506296
2017-11-25 15:22:00 While active INO1 is associated with Cdk8(-) Mediator, during INO1 transcriptional memory, Cdk8(+) Mediator recruits poised RNAPII PIC lacking the Kin28 CTD kinase. 27336723
2015-02-14 14:07:00 with Srb10 clearing mostly inactive Gcn4 molecules at the promoter that are enriched for sumoylation of the activation domain, and Pho85 clearing molecules unbound to the UAS that include both fully functional and inactive Gcn4 species. 25079372
2014-04-26 10:41:00 the detailed architecture of Cdk8 module, and suggest the Cdk8 module could positively regulate transcription by modulating Mediator conformation. 24043446
2014-04-19 11:02:00 The function of the Mediator tail module component Med3, which is required for transcription activation, is suppressed by the kinase activity of the Cdk8 module. 24550274

名称对应

Type IDs
Synonymous CDK8, GIG2, NUT7, RYE5, SRB10, SSX7, UME5, URR1
Gene
UniProtKB-ID: SSN3_YEAST
UniprotKB: P39073
UniParc: UPI0000053162
EMBL: L27151, BK006949, U20222, U44030
EnsemblGenome: YPL042C
KO: sce:YPL042C
Nucleutide sequences
EMBL-CDS: DAA11387.1, AAA35193.1, AAB68178.1, AAC13785.1
EnsemblGenome_TRS: YPL042C_mRNA
Protein sequencees
EnsemblGenome_PRO: YPL042C
RefSeq: NP_015283.1
Others
UniRef100: UniRef100_P39073
UniRef90: UniRef90_P39073
UniRef50: UniRef50_P39073

全选

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研究热度

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