| Type | Description |
|---|---|
| Definition | delta 4-desaturase, sphingolipid 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-12 16:01:00 | Sphingolipid Modulation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal. | 31631013 |
| 2020-07-25 11:55:00 | DEGS1 variant causes neurological disorder. | 31186544 |
| 2020-02-29 11:28:00 | DEGS1 dysfunction as the cause of a sphingolipid disorder with hypomyelination and degeneration of both the central and peripheral nervous systems. | 30620338 |
| 2019-02-16 11:02:00 | Pratensein induced both FADS1 and FADS2 in differentiated 3T3-L1 cells and DEGS1 was increased by treatment with apigenin, genistein, luteolin, orobol, and quercetin. In conclusion, pratensein may be an interesting test compound for further studies in vitro and in vivo on omega-3 synthesis since it induces its rate-limiting enzyme FADS2 | 30365230 |
| 2018-03-03 11:16:00 | DES1 plays a key role in palmitic acid-mediated caspase 9 and caspase 3 activation. | 27364952 |
| Type | IDs |
|---|---|
| Synonymous | DEGS, DEGS-1, DES1, Des-1, FADS7, MIG15, MLD |
| Gene |
UniProtKB-ID:
DEGS1_HUMAN,
A0A024R3P1_HUMAN
UniprotKB:
O15121,
A0A024R3P1
UniParc:
UPI000007137B
EMBL:
AY423730,
AF002668,
CH471098,
BC000961,
AF466375
Ensembl:
ENSG00000143753
KO:
hsa:8560
|
| Nucleutide sequences |
EMBL-CDS:
AAS00493.1,
EAW69711.1,
AAM12531.1,
AAB62238.1,
AAH00961.1,
EAW69712.1
Gene_ORFName:
MIG15,
hCG_1736748
Ensembl_TRS:
ENST00000323699,
ENST00000391877
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000316476,
ENSP00000375749
RefSeq:
XP_016858137.1,
NP_001308471.1,
NP_003667.1,
NP_001308470.1
|
| Others |
UniRef100:
UniRef100_O15121
UniRef90:
UniRef90_O15121
UniRef50:
UniRef50_O15121
UniGene:
Hs.299878
CCDS:
CCDS1540.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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