| Type | Description |
|---|---|
| Definition | Spp1p |
| Date | Results | Publications |
|---|---|---|
| 2020-03-21 10:31:00 | Structural basis for histone H3K4me3 recognition by the N-terminal domain of the PHD finger protein Spp1. | 31253666 |
| 2019-09-28 11:41:00 | results indicate that "chromosomal turnover rate" is a major molecular determinant of Spp1 function in the framework of meiotic chromatin structure that prepares recombination initiation sites for break formation. | 30037925 |
| 2018-07-21 11:48:00 | A model where Spp1 works in three ways to promote recombination initiation: first by depositing histone H3K4 methylation (Set1 complex), next by "reading" and protecting histone H3K4 methylation, and finally by making the link with the chromosome axis (Mer2-Spp1 complex). This work deciphers the precise roles of Spp1 in meiotic recombination. | 29444071 |
| 2015-05-16 11:25:00 | Spp1 regulates the catalytic activity of the enzyme (Set1) and mediates its biological effect (meiotic DSB formation) independently of the single Set1 Complex. | 23511748 |
| 2013-03-09 12:17:00 | Spp1, a conserved member of the histone H3K4 methyltransferase Set1 complex, is required for normal levels of double strand breaks formation and is associated with chromosome axes during meiosis. | 23246437 |
| Type | IDs |
|---|---|
| Synonymous | CPS40, SAF41 |
| Gene |
UniProtKB-ID:
SPP1_YEAST
UniprotKB:
Q03012
UniParc:
UPI0000052FF7
EMBL:
U43703,
BK006949
EnsemblGenome:
YPL138C
KO:
sce:YPL138C
|
| Nucleutide sequences |
EMBL-CDS:
AAB68222.1,
DAA11296.1
EnsemblGenome_TRS:
YPL138C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YPL138C
RefSeq:
NP_015187.1
|
| Others |
UniRef100:
UniRef100_Q03012
UniRef90:
UniRef90_Q03012
UniRef50:
UniRef50_Q03012
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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