| Type | Description |
|---|---|
| Definition | mismatch repair protein MLH3 |
| Date | Results | Publications |
|---|---|---|
| 2018-02-03 10:06:00 | mlh3Delta showed approximately 30% genome-wide reduction in crossovers and loss of the obligate crossover, but nonexchange chromosomes were efficiently segregated. | 28315832 |
| 2017-09-23 12:30:00 | Our observations provide a structure-function map for Mlh3 that reveals the importance of protein-protein interactions in regulating Mlh1-Mlh3's enzymatic activity. They also illustrate how defective meiotic components can alter the fate of meiotic recombination intermediates, providing new insights for how meiotic recombination pathways are regulated. | 28827832 |
| 2014-04-26 13:05:00 | observations support a direct role for an Mlh1-Mlh3 endonuclease activity in resolving recombination intermediates and in DNA mismatch repair. | 24403070 |
| 2014-04-26 12:33:00 | Mlh1-Mlh3 prefers to bind the open unstacked Holliday junction form. | 24443562 |
| 2013-06-29 12:46:00 | Genetic analysis of mlh3 mutations reveals interactions between crossover promoting factors during meiosis in baker's yeast. | 23316435 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
MLH3_YEAST
UniprotKB:
Q12083
UniParc:
UPI0000069F72
EMBL:
BK006949,
X96770,
Z73520
EnsemblGenome:
YPL164C
KO:
sce:YPL164C
|
| Nucleutide sequences |
EMBL-CDS:
CAA65557.1,
CAA97869.1,
DAA11270.1
Gene_ORFName:
P2550
EnsemblGenome_TRS:
YPL164C_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YPL164C
RefSeq:
NP_015161.1
|
| Others |
UniRef100:
UniRef100_Q12083
UniRef90:
UniRef90_Q12083
UniRef50:
UniRef50_Q12083
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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