| Type | Description |
|---|---|
| Definition | Acm1p |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 11:23:00 | The anaphase-promoting complex/cyclosome (APC/C) is suppressed by the small pseudosubstrate inhibitor Acm1. Acm1 D-box extension inhibits reaction processivity by perturbing the normal interaction with Doc1/Apc10. These results reveal a simple, elegant mode of pseudosubstrate inhibition that combines high-affinity activator binding with specific disruption of Doc1/Apc10 function in processive ubiquitylation. | 31562243 |
| 2013-08-31 10:13:00 | the structure of an Acm1-Cdh1 complex | 23707760 |
| 2012-09-01 10:41:00 | Cells lacking Acm1 have defects in nuclear positioning and spindle morphology during mitosis. | 22189709 |
| 2010-01-21 00:00:00 | Cdc28 serves dual roles in inhibiting Cdh1-dependent anaphase-promoting complex (APC) activity during the cell cycle: stabilization of the Cdh1 inhibitor Acm1 and direct phosphorylation of Cdh1 to prevent its association with the APC. | 18519589 |
| 2010-01-21 00:00:00 | Data show that in budding yeast the activation of APC(Cdh1) is controlled in part by destruction of the Cdh1 inhibitor Acm1. | 18498748 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
ACM1_YEAST
UniprotKB:
Q08981
UniParc:
UPI000006C283
EMBL:
Z73623,
AY558139,
BK006949
EnsemblGenome:
YPL267W
KO:
sce:YPL267W
|
| Nucleutide sequences |
EMBL-CDS:
CAA98002.1,
DAA11169.1,
AAS56465.1
EnsemblGenome_TRS:
YPL267W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YPL267W
RefSeq:
NP_015056.1
|
| Others |
UniRef100:
UniRef100_Q08981
UniRef90:
UniRef90_Q08981
UniRef50:
UniRef50_Q08981
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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