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855788 POP2

855788

POP2

CCR4-NOT core DEDD family RNase subunit POP2

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition CCR4-NOT core DEDD family RNase subunit POP2

研究结论

Date Results Publications
2021-01-23 13:04:00 CAF-1 and Rtt101p function within the replication-coupled chromatin assembly network to promote H4 K16ac, preventing ectopic silencing. 33284793
2020-02-22 10:52:00 Pan2 does not form canonical base-specific contacts. Instead, it recognizes the intrinsic stacked, helical conformation of poly(A) RNA. Using a fully reconstituted biochemical system, the study shows that disruption of this structure-for example, by incorporation of guanosine into poly(A)-inhibits deadenylation by both Pan2 and Caf1. 31110294
2018-01-13 12:46:00 The authors show that yeast chromatin assembly factor 1 binding to a histone H3-H4 dimer activates the Cac1 winged helix domain interaction with DNA. This drives the formation of a transient intermediate containing two chromatin assembly factor 1 complexes, each associated with one H3-H4 dimer. Here, the (H3-H4)2 tetramer is formed and deposited onto DNA. 28315523
2018-01-13 12:46:00 Here, the authors report that yeast chromatin assembly factor 1 (CAF1), a conserved histone chaperone complex that deposits H3-H4 during DNA replication, binds a single H3-H4 heterodimer in solution. 28315525
2013-04-06 10:46:00 MIF4G domain positioned centrally within the Not1 protein recognizes Caf1, which in turn binds the LRR domain of Ccr4 and tethers the Ccr4 nuclease domain 22959269

名称对应

Type IDs
Synonymous CAF1
Gene
UniProtKB-ID: POP2_YEAST
UniprotKB: P39008
UniParc: UPI0000052DFA
EMBL: AY692792, BK006947, M88607, D12808, D12807, Z71667
EnsemblGenome: YNR052C
KO: sce:YNR052C
Nucleutide sequences
EMBL-CDS: BAA02246.1, DAA10593.1, BAA02247.1, CAA96333.1, AAA34832.1, AAT92811.1
Gene_ORFName: N3470
EnsemblGenome_TRS: YNR052C_mRNA
Protein sequencees
EnsemblGenome_PRO: YNR052C
RefSeq: NP_014450.3
Others
UniRef100: UniRef100_P39008
UniRef90: UniRef90_P39008
UniRef50: UniRef50_P39008

全选

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研究热度

热点单位
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