| Type | Description |
|---|---|
| Definition | ribosome dissociation factor DOM34 |
| Date | Results | Publications |
|---|---|---|
| 2018-09-08 12:04:00 | analysis establishes the structural foundation for the recognition of aberrantly stalled 80S ribosomes by the Dom34.Hbs1.GTP complex during Dom34-mediated mRNA surveillance pathways | 27995908 |
| 2017-04-29 12:22:00 | Translational effects of Dom34 required the 5'-UTR of the PMT1 transcript, which bound recombinant Dom34 directly at a CA/AC-rich sequence and regulated in vitro translation. Polysomal profiling revealed that Dom34 stimulates general translation moderately, but that it is especially required for translation of transcripts encoding Pmt isoforms 1, 4 and 6. | 27768707 |
| 2014-05-31 11:09:00 | Study found that Dom34 rescues ribosomes that stall at the 3' end of mRNAs that are truncated. Dom34 rescues ribosomes in the 3' untranslated region of many genes. Surprisingly, many ribosomes populate this noncoding region, and these ribosomes seem to move along the mRNA without recognizing codons, presumably not translating, and eventually arrest. | 24581494 |
| 2013-03-02 10:57:00 | Roles of dom34:hbs1 in nonstop protein clearance from translocators for normal organelle protein influx. | 22981232 |
| 2012-07-28 11:33:00 | Dom34:Hbs1 facilitates the decay of nonstop mRNAs from the 3' end by exosomes and is required for the complete degradation of nonstop mRNA decay intermediates. | 22503425 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
DOM34_YEAST
UniprotKB:
P33309
UniParc:
UPI0000168400
EMBL:
L11277,
Z71277,
X77114,
BK006947
EnsemblGenome:
YNL001W
KO:
sce:YNL001W
|
| Nucleutide sequences |
EMBL-CDS:
AAA34575.1,
CAA95860.1,
CAA54375.1,
DAA10542.1
Gene_ORFName:
N2016
EnsemblGenome_TRS:
YNL001W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YNL001W
RefSeq:
NP_014397.1
|
| Others |
UniRef100:
UniRef100_P33309
UniRef90:
UniRef90_P33309
UniRef50:
UniRef50_P33309
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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