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855680 SLM2

855680

SLM2

phosphatidylinositol 4,5-bisphosphate-binding protein

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition phosphatidylinositol 4,5-bisphosphate-binding protein

研究结论

Date Results Publications
2013-03-02 11:40:00 Slm1/SLm2 and TORC2-dependent phosphorylation of Ypk1 is coupled to the biosynthesis of complex sphingolipids and to their levels within the plasma membrane. 22895050
2012-03-31 10:46:00 TORC2 has been shown previously to negatively regulate calcineurin in part by phosphorylating two related proteins, Slm1 and Slm2, which associate with the PM via plextrin homology domains 22307609
2010-01-21 00:00:00 Slm proteins are subject to regulation by multiple signals, including PI4,5P(2), TORC2, and sphingolipids, and may thus integrate inputs from different signaling pathways to temporally and spatially control actin polarization 17101780
2010-01-21 00:00:00 Slm1 and Slm2 integrate inputs from the Phosphatidylinositol-4,5-bisphosphate and TORC2 to modulate polarized actin assembly and growth 15689497
2010-01-21 00:00:00 Data suggest that Slm1 and Slm2 define a molecular link between phosphoinositide and sphingolipid signaling and thereby regulate actin cytoskeleton organization. 16847337

名称对应

Type IDs
Synonymous LIT1
Gene
UniProtKB-ID: SLM2_YEAST
UniprotKB: P53955
UniParc: UPI000013BB14
EMBL: Z71323, AY692658, U12141, BK006947, X94547, AY899254
EnsemblGenome: YNL047C
KO: sce:YNL047C
Nucleutide sequences
EMBL-CDS: AAX83939.1, CAA95915.1, AAA99665.1, DAA10498.1, CAA64235.1, AAT92677.1
Gene_ORFName: YNL2515P, N2515
EnsemblGenome_TRS: YNL047C_mRNA
Protein sequencees
EnsemblGenome_PRO: YNL047C
RefSeq: NP_014351.3
Others
UniRef100: UniRef100_P53955
UniRef90: UniRef90_P53955
UniRef50: UniRef50_P53955

全选

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研究热度

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