例如:"NBL1", "4681", "drought"
收藏
855642 PMS1

855642

PMS1

ATP-binding mismatch repair protein

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition ATP-binding mismatch repair protein

研究结论

Date Results Publications
2020-08-01 14:20:00 Results provide evidence that the PMS1 gene encoding one of the crucial components of the mismatch repair, is required for transcriptional repression at silent mating-type loci and telomeres. 32469861
2019-08-31 11:31:00 Mlh1-Pms1 complexes with shorter IDRs that disrupt MMR retain wild-type DNA binding affinity but are impaired for diffusion on both naked and nucleosome-coated DNA. Moreover, the IDRs also regulate the adenosine triphosphate hydrolysis and nuclease activities that are encoded in the structured N- and C-terminal domains of the complex 30541127
2019-03-02 11:32:00 Genotyping analysis indicated that MLH1-PMS1 incompatibility was the major driver of mutation rate in the isolates. The variation in the mutation rate of incompatible spore clones could be due to background suppressors and enhancers, as well as aneuploidy seen in the spore clones. 30348651
2015-02-21 12:03:00 Two mutants of MutLalpha, pms1-G882E and pms1-H888R, repair deletion mispairs but not insertion mispairs. 24204320
2014-05-24 12:01:00 a comparative study of Msh2-Msh3 and Msh2-Msh6 for mispair binding, sliding clamp formation, and Mlh1-Pms1 recruitment 24550389

名称对应

Type IDs
Gene
UniProtKB-ID: PMS1_YEAST
UniprotKB: P14242
UniParc: UPI00003596AF
EMBL: AF458974, AF458971, DQ356631, DQ356628, Z71358, AF458969, BK006947, DQ356629, X89016, DQ356630, Z71357, X86470, DQ115393, AF458973, DQ356632, AF458976, M29688, AF458977
EnsemblGenome: YNL082W
KO: sce:YNL082W
Nucleutide sequences
EMBL-CDS: AAZ22526.1, CAA61428.1, ABC86935.1, DAA10463.1, AAM00563.1, AAM00545.1, ABC86936.1, AAM00569.1, AAA34885.1, AAM00533.1, AAM00551.1, ABC86933.1, CAA95956.1, CAA60176.1, ABC86934.1, ABC86932.1, AAM00521.1, CAA95957.1
Gene_ORFName: N2317
EnsemblGenome_TRS: YNL082W_mRNA
Protein sequencees
EnsemblGenome_PRO: YNL082W
RefSeq: NP_014317.4
Others
UniRef100: UniRef100_P14242
UniRef90: UniRef90_P14242
UniRef50: UniRef50_P14242

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员