| Type | Description |
|---|---|
| Definition | DNA-directed DNA polymerase alpha catalytic subunit POL1 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-14 10:36:00 | Here the authors show that Ctf4 tightly dimerizes CMG helicase, with an extensive interface involving Psf2, Cdc45, and Sld5. Interestingly, Ctf4 binds only one Pol alpha-primase. Thus, Ctf4 may have evolved as a trimer to organize two helicases and one Pol alpha-primase into a replication factory. | 31589141 |
| 2019-10-05 11:13:00 | chromatin-derived histone complexes can be bound simultaneously by Mcm2, Pol alpha and the histone chaperone FACT that is also a replisome component. | 30104407 |
| 2019-04-20 11:29:00 | ur results support a model whereby parental (H3-H4)2 complexes displaced from nucleosomes by DNA unwinding at replication forks are transferred by the CMG-Ctf4-Polalph acomplex to lagging-strand DNA for nucleosome assembly at the original location. | 30244834 |
| 2018-03-31 12:05:00 | Core Factor's intrinsic mobility correlates well with different conformational states of the Pol I cleft, in addition to the stabilization of either Rrn7 N-terminal domain near Pol I wall or the tandem winged helix domain of A49 at a partially overlapping location. | 28623663 |
| 2017-10-21 11:49:00 | An intact Mcm10 coiled-coil interaction surface is important for origin melting, helicase assembly and the recruitment of Pol-alpha to Mcm2-7. | 28510759 |
| Type | IDs |
|---|---|
| Synonymous | CDC17, CRT5, HPR3 |
| Gene |
UniProtKB-ID:
DPOA_YEAST
UniprotKB:
P13382
UniParc:
UPI0000052DF8
EMBL:
J03268,
Z71378,
Z50161,
Z12126,
BK006947
EnsemblGenome:
YNL102W
KO:
sce:YNL102W
|
| Nucleutide sequences |
EMBL-CDS:
CAA78111.1,
CAA95978.1,
AAA34888.1,
DAA10443.1,
CAA90524.1
Gene_ORFName:
N2181
EnsemblGenome_TRS:
YNL102W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YNL102W
RefSeq:
NP_014297.3
|
| Others |
UniRef100:
UniRef100_P13382
UniRef90:
UniRef90_P13382
UniRef50:
UniRef50_P13382
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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