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8556 CDC14A

8556

CDC14A

cell division cycle 14A

protein-coding

Homo sapiens

基因描述

Type Description
Definition cell division cycle 14A

研究结论

Date Results Publications
2021-02-02 13:24:00 When transcripts matter: delineating between non-syndromic hearing loss DFNB32 and hearing impairment infertile male syndrome (HIIMS). 32231217
2020-07-04 11:45:00 The study functionally characterizes two variants and provides further confirmatory evidence that CDC14A is associated with a rare form of hereditary hearing loss. 31906439
2019-10-19 12:29:00 Point to differences in Cdk1-mediated mechanisms of regulation between human and yeast Cdc14 orthologues. 30089874
2019-08-17 12:46:00 we show that drebrin and hCDC14A regulate the recruitment of the actin organizer Arp2 to centrosomes. In addition, during ciliogenesis hCDC14A also regulates endocytosis and targeting of myosin Va vesicles to the basal body in a drebrin-independent manner, indicating that it impacts primary cilia formation in a multilayered manner. 30467237
2019-01-05 11:37:00 CDC14A activity is necessary for hearing and male fertility. 29293958

名称对应

Type IDs
Synonymous DFNB105, DFNB32, DFNB35, cdc14, hCDC14
Gene
UniProtKB-ID: CC14A_HUMAN, Q59EF4_HUMAN, B4DY86_HUMAN, A0A0U1RQX7_HUMAN, A0A2R8YDJ8_HUMAN
UniprotKB: Q9UNH5, Q59EF4, B4DY86, A0A0U1RQX7, A0A2R8YDJ8
UniParc: UPI00017A8172, UPI00004F6E6E, UPI000006FD73, UPI00002053C5, UPI000007431E, UPI0002065012, UPI0000071036, UPI0001577E93, UPI000006EC22
EMBL: AF122013, AF064103, AF000367, AC104457, BC093918, BC038979, AL589990, AF064102, CH471097, BC093916, AB209857, AK302310, AY623111, DQ530256
Ensembl: ENSG00000079335
KO: hsa:8556
Nucleutide sequences
EMBL-CDS: ABF74568.1, AAT38107.1, AAH38979.1, AAD49217.1, AAB88277.1, EAW72959.1, AAH93918.1, AAC16659.1, EAW72958.1, EAW72956.1, AAC16660.1, AAH93916.1, BAD93094.1, BAG63648.1
Ensembl_TRS: ENST00000336454, ENST00000361544, ENST00000370124, ENST00000644813, ENST00000635056, ENST00000644676
Protein sequencees
Ensembl_PRO: ENSP00000359142, ENSP00000336739, ENSP00000496374, ENSP00000354916, ENSP00000489217, ENSP00000494661
RefSeq: XP_024306272.1, NP_003663.2, NP_001306141.1, XP_005271353.1, XP_011540643.1, NP_201569.1, NP_201570.1, XP_016858135.1, XP_011540642.1, XP_024306274.1, XP_005271351.1, NP_001306139.1, XP_011540647.1, XP_024306271.1, NP_001306140.1, XP_024306273.1, XP_016858136.1
Others
UniRef100: UniRef100_A0A2R8YDJ8, UniRef100_Q9UNH5, UniRef100_Q59EF4, UniRef100_B4DY86
UniRef90: UniRef90_Q9UNH5, UniRef90_E2RQI1
UniRef50: UniRef50_Q9UNH5, UniRef50_Q9UNH5-5
UniGene: Hs.127411
CCDS: CCDS771.1, CCDS770.1, CCDS86000.1, CCDS769.1

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