| Type | Description |
|---|---|
| Definition | adenylate cyclase-binding protein |
| Date | Results | Publications |
|---|---|---|
| 2020-03-07 11:08:00 | Cyclase-associated protein (CAP) and Cofilin synergize to processively depolymerize actin filament pointed ends at a rate 330-fold faster than spontaneous depolymerization. Single molecule imaging further reveals that hexameric CAP molecules interact with the pointed ends of Cofilin-decorated filaments for several seconds at a time, removing approximately 100 actin subunits per binding event. | 31757952 |
| 2016-12-17 11:28:00 | in vivo roles of Srv2p in the regulation of the actin cytoskeleton during clathrin-mediated endocytosis. | 26604224 |
| 2016-03-19 12:00:00 | Data show that Twinfilin and Srv2 proteins accelerate depolymerization from actin filament ends. | 26458246 |
| 2013-06-08 13:03:00 | Data indicate that the combined activities of cofilin and Srv2/CAP lead to enhanced filament severing and support an emerging view that actin disassembly is controlled not by cofilin alone, but by a more complex set of factors working in concert. | 23135996 |
| 2010-01-21 00:00:00 | Data suggest a revised model for the mechanism by which Srv2 promotes actin turnover, in which coordinated activities of its N- and C-terminal halves catalyze sequential steps in recycling cofilin and actin monomers. | 19201756 |
| Type | IDs |
|---|---|
| Synonymous | CAP |
| Gene |
UniProtKB-ID:
CAP_YEAST
UniprotKB:
P17555
UniParc:
UPI0000052E5C
EMBL:
M32663,
Z46843,
BK006947,
M58284,
Z71414
EnsemblGenome:
YNL138W
KO:
sce:YNL138W
|
| Nucleutide sequences |
EMBL-CDS:
CAA86887.1,
AAA63569.1,
AAA35094.1,
DAA10410.1,
CAA96020.1
Gene_ORFName:
N1838,
N1210
EnsemblGenome_TRS:
YNL138W_mRNA
|
| Protein sequencees |
EnsemblGenome_PRO:
YNL138W
RefSeq:
NP_014261.1
|
| Others |
UniRef100:
UniRef100_P17555
UniRef90:
UniRef90_P17555
UniRef50:
UniRef50_P17555
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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