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855580 MEP2

855580

MEP2

ammonium permease MEP2

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition ammonium permease MEP2

研究结论

Date Results Publications
2020-05-16 11:56:00 Study shows that S. cerevisiae filamentation is intimately related to Mep2 transport activity. Mep2 variants lacking the C-terminal domain but containing specific pore mutations enabling transport can still allow filamentation induction. Mep2H194E pore variant shows increased competence to acidify the submembrane pH while losing the signaling capability. 32069286
2016-09-10 10:27:00 X-ray crystal structures are being reported of the Mep2 orthologues from Saccharomyces cerevisiae and Candida albicans showing that under nitrogen-sufficient conditions the transporters are not phosphorylated and present in closed, inactive conformations. 27088325
2010-01-21 00:00:00 Mep2-like proteins are nutrient sensing transceptors that govern cellular differentiation 18434596
2010-01-21 00:00:00 The growth impairment of cells lacking Npr1 on many nitrogen sources is shared by cells deprived of the three Mep proteins and is a consequence of deficient ammonium retrieval. 17493133
2010-01-21 00:00:00 an ammonium permease MEP2-based sensing mechanism for rapid activation of the protein kinase A pathway 16468990

名称对应

Type IDs
Gene
UniProtKB-ID: MEP2_YEAST
UniprotKB: P41948
UniParc: UPI000012EF06
EMBL: X83608, Z71418, Z46843, BK006947
EnsemblGenome: YNL142W
KO: sce:YNL142W
Nucleutide sequences
EMBL-CDS: CAA86884.1, CAA58587.1, DAA10406.1, CAA96025.1
Gene_ORFName: N1207, N1820
EnsemblGenome_TRS: YNL142W_mRNA
Protein sequencees
EnsemblGenome_PRO: YNL142W
RefSeq: NP_014257.1
Others
UniRef100: UniRef100_P41948
UniRef90: UniRef90_P41948
UniRef50: UniRef50_P41948

全选

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研究热度

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