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855561 CBK1

855561

CBK1

serine/threonine protein kinase CBK1

protein-coding

Saccharomyces cerevisiae S288c

基因描述

Type Description
Definition serine/threonine protein kinase CBK1

研究结论

Date Results Publications
2019-10-26 11:43:00 Fir1 is an intrinsically disordered protein localized to the cytokinesis site that is degraded upon septum completion but stabilized when septation is aberrant. Fir1 protects cytokinesis in part by inhibiting a separation-specific exocytosis function of the Cbk1, a key component of "hippo" signaling that induces mother-daughter separation. 30455324
2016-04-16 10:17:00 Cbk1-Mob2 complex shows a novel coactivator-organized activation region that may be unique to NDR/LATS kinases, in which a key regulatory motif apparently shifts from an inactive binding mode to an active one upon phosphorylation 25966461
2012-08-04 10:24:00 Cbk1 and Bck2 are required for Mpk1 activation during heat shock and cell wall stress and for Mpk1 dephosphorylation during heat shock adaptation. 22031291
2011-03-05 10:42:00 propose that Cdc14 coordinates cell separation with mitotic exit via FEAR-initiated phosphorylation of the Cbk1 HM site and MEN-activated reversal of mitotic CDK phosphorylations that block both Cbk1 and Ace2 function 21135117
2011-02-26 10:24:00 Data show that Ace2's nuclear localization is maintained by continuous Cbk1 activity and that inhibition of the kinase leads to immediate loss of phosphorylation and export to the cytoplasm. 20573982

名称对应

Type IDs
Gene
UniProtKB-ID: CBK1_YEAST
UniprotKB: P53894
UniParc: UPI00001271A4
EMBL: X92517, BK006947, Z71437
EnsemblGenome: YNL161W
KO: sce:YNL161W
Nucleutide sequences
EMBL-CDS: CAA96048.1, DAA10388.1, CAA63278.1
Gene_ORFName: N1727
EnsemblGenome_TRS: YNL161W_mRNA
Protein sequencees
EnsemblGenome_PRO: YNL161W
RefSeq: NP_014238.3
Others
UniRef100: UniRef100_P53894
UniRef90: UniRef90_P53894
UniRef50: UniRef50_Q5AP53

全选

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研究热度

热点单位
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